(Q46862244)

25 December 2017

title

Targeting c-KIT, PDGFR in cancer of unknown primary: a screening study for molecular markers of benefit (English)

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25 December 2017

8

G Fountzilas

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25 December 2017

author name string

L Dova

1

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25 December 2017

G Pentheroudakis

2

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25 December 2017

V Golfinopoulos

3

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V Malamou-Mitsi

4

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25 December 2017

I Georgiou

5

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G Vartholomatos

6

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A Ntemou

7

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N Pavlidis

9

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publication date

7 December 2007

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25 December 2017

Journal of Cancer Research and Clinical Oncology

published in

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25 December 2017

volume

134

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issue

6

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25 December 2017

page(s)

697-704

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25 December 2017

https://scigraph.springernature.com/pub.10.1007/s00432-007-0341-7

exact match

0 references

cites work

Lack of clinical efficacy of imatinib in metastatic melanoma

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12 December 2020

Cancer of unknown primary site: missing primary or missing biology?

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12 December 2020

KIT and platelet-derived growth factor receptor alpha tyrosine kinase gene mutations and KIT amplifications in human solid tumors

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12 December 2020

Cancer. Encouraging results for second-generation antiangiogenesis drugs

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12 December 2020

Perspectives for targeted therapies in cancer of unknown primary site

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12 December 2020

Expression of platelet-derived growth factor-alpha alpha receptor is associated with tumor progression in clear cell renal cell carcinoma

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12 December 2020

Molecular Analysis of c-KitandPDGFRAin GISTs Diagnosed by EUS

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12 December 2020

Gastrointestinal stromal tumors (GIST): C-kit mutations, CD117 expression, differential diagnosis and targeted cancer therapy with imatinib

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12 December 2020

Expression and mutational analysis of tyrosine kinase receptors c-kit, PDGFRalpha, and PDGFRbeta in ovarian cancers

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12 December 2020

Biology of gastrointestinal stromal tumors.

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12 December 2020

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

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12 December 2020

PDGFRA activating mutations in gastrointestinal stromal tumors.

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12 December 2020

Global profiling of EGFR gene mutation, amplification, regulation and tissue protein expression in unknown primary carcinomas: to target or not to target?

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12 December 2020

Kit as a human oncogenic tyrosine kinase

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12 December 2020

Strong PDGFRA positivity is seen in GISTs but not in other intra-abdominal mesenchymal tumors: Immunohistochemical and mutational analyses

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12 December 2020

Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression

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12 December 2020

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand

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12 December 2020

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

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12 December 2020

Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

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12 December 2020

PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib

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12 December 2020

Sunitinib in patients with metastatic renal cell carcinoma

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12 December 2020

Lack of c-kit exon 11 activating mutations in c-KIT/CD117-positive SCLC tumour specimens

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12 December 2020

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

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12 December 2020

cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor

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12 December 2020

Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group

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12 December 2020

Expression of platelet-derived growth factor (PDGF) and PDGF receptors in human malignant mesothelioma in vitro and in vivo

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12 December 2020

Prevalence of KIT expression in human tumors

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12 December 2020

Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial

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12 December 2020

Immunohistochemical and mutational analysis of PDGF and PDGFR in desmoid tumours: is there a role for tyrosine kinase inhibitors in c-kit-negative desmoid tumours?

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12 December 2020

Mechanism of action and in vivo role of platelet-derived growth factor

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12 December 2020

KIT activation is a ubiquitous feature of gastrointestinal stromal tumors

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12 December 2020

Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

1 reference

12 December 2020

Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma

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12 December 2020

Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors

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12 December 2020

Platelet-derived growth factor (PDGF) and glial tumorigenesis

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12 December 2020

Phase II study of imatinib in patients with small cell lung cancer.

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12 December 2020

Expression of protein tyrosine kinases in head and neck squamous cell carcinomas

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12 December 2020

Expression of platelet-derived growth factor-AA is associated with tumor progression in osteosarcoma

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12 December 2020

10.1007/S00432-007-0341-7

Identifiers

DOI

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25 December 2017

PubMed ID

18064489

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25 December 2017