(Q46865480)

English

Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle

scientific article published in December 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

lipopolysaccharide

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toll-like receptor

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1 reference

based on heuristic

inferred from title

insulin resistance

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author name string

M S Radin

1

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

S Sinha

2

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

B A Bhatt

3

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

N Dedousis

4

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

R M O'Doherty

5

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

publication date

1 December 2007

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

51

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

2

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

336-346

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

C-reactive protein, insulin resistance, central obesity, and coronary heart disease risk in Indian Asians from the United Kingdom compared with European whites.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-007-0861-3

21 January 2018

Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors

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https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

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Inflammatory status and insulin resistance

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https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

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A genetic basis for the "Adonis" phenotype of low adiposity and strong bones

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IKK-beta links inflammation to obesity-induced insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

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Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of insulin-stimulated skeletal muscle glucose uptake in conscious rat using isotopic glucose analogs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of fat-induced insulin resistance by salicylate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A central role for JNK in obesity and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR4 links innate immunity and fatty acid-induced insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver triglyceride secretion and lipid oxidative metabolism are rapidly altered by leptin in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor signal transduction and the tailoring of innate immunity: a role for Mal?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate immune sensing and its roots: the story of endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TIRAP: an adapter molecule in the Toll signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide content is increased in skeletal muscle from obese insulin-resistant humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity is associated with macrophage accumulation in adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of toll-like receptors in changes in gene expression and NF-kappa B activation in mouse hepatocytes stimulated with lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inferences, questions and possibilities in Toll-like receptor signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diet-induced obesity and acute hyperlipidemia reduce IkappaBalpha levels in rat skeletal muscle in a fiber-type dependent manner.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/18060381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-007-0861-3

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18060381

ResearchGate publication ID

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