(Q46865803)

25 December 2017

title

Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1. (English)

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25 December 2017

2

Arthur I Cederbaum

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25 December 2017

author name string

Pengfei Gong

series ordinal

1

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25 December 2017

language of work or name

English

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publication date

1 January 2006

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25 December 2017

published in

Hepatology

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25 December 2017

volume

43

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25 December 2017

issue

1

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25 December 2017

page(s)

144-153

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25 December 2017

Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis

cites work

1 reference

7 January 2021

Antioxidant-inducible genes

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7 January 2021

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

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7 January 2021

Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer

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7 January 2021

Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

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7 January 2021

Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

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7 January 2021

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

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7 January 2021

The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress

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7 January 2021

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

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7 January 2021

Cytochrome P450IIE1: roles in nitrosamine metabolism and mechanisms of regulation

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7 January 2021

Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation

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7 January 2021

Fish oil, alcohol, and liver pathology: role of cytochrome P450 2E1

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7 January 2021

Markedly enhanced cytochrome P450 2E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-ethanol-fed rats

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7 January 2021

CYP2E1: Biochemistry, Toxicology, Regulation and Function in Ethanol-Induced Liver Injury

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7 January 2021

Oxidative stress, toxicology, and pharmacology of CYP2E1.

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7 January 2021

Oxidative stress and cytotoxicity induced by ferric-nitrilotriacetate in HepG2 cells that express cytochrome P450 2E1.

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7 January 2021

Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P4502E1.

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7 January 2021

CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase.

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7 January 2021

Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway

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7 January 2021

Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress.

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7 January 2021

Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity

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7 January 2021

Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells

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7 January 2021

Halogenated compounds as inducers of lipid peroxidation in tissue slices

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7 January 2021

Overexpression of catalase in cytosolic or mitochondrial compartment protects HepG2 cells against oxidative injury

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7 January 2021

Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation

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7 January 2021

Inhibitory effects of heavy metals on transcription factor Sp1

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7 January 2021

Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite

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7 January 2021

Role of cytochrome P-450 IIE1 and catalase in the oxidation of acetonitrile to cyanide

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7 January 2021

Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1.

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7 January 2021

Implication of free radical mechanisms in ethanol-induced cellular injury

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7 January 2021

Current concepts in the pathogenesis of alcoholic liver injury

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7 January 2021

Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole

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7 January 2021

Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice

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7 January 2021

Effect of ethanol and high-fat feeding on hepatic gamma-glutamylcysteine synthetase subunit expression in the rat

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7 January 2021

Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity

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7 January 2021

Identifiers

DOI

10.1002/HEP.21004

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25 December 2017

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25 December 2017