(Q46867360)

English

The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity

scientific article published on 5 December 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

author name string

M L Woolley

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

D J Pemberton

2

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

S Bate

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

C Corti

4

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

D N C Jones

5

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

publication date

5 December 2007

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

Psychopharmacology

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

196

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

431-440

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenyl-tetrazolyl acetophenones: discovery of positive allosteric potentiatiors for the metabotropic glutamate 2 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A case-control study of the relationship between the metabotropic glutamate receptor 3 gene and schizophrenia in the Chinese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative splicing of human metabotropic glutamate receptor 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor 3 (GRM3) gene variation is not associated with schizophrenia or bipolar affective disorder in the German population

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of effect of LY314582 (a group 2 metabotropic glutamate receptor agonist) on phencyclidine-induced locomotor activity in metabotropic glutamate receptor 2 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Habituation deficits induced by metabotropic glutamate receptors 2/3 receptor blockade in mice: reversal by antipsychotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neurotransmitter release by metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s).

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): analysis of association with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the mGluR2/3 agonist LY379268 on ketamine-evoked behaviours and neurochemical changes in the dentate gyrus of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical pharmacology of mGlu2/3 receptor agonists: novel agents for schizophrenia?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptors: electrophysiological properties and role in plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LABORAS™: Initial pharmacological validation of a system allowing continuous monitoring of laboratory rodent behaviour

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of mGlu2 or mGlu3 receptor deletions on mGlu2/3 receptor agonist (LY354740)-induced brain c-Fos expression: specific roles for mGlu2 in the amygdala and subcortical nuclei, and mGlu3 in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzazoles as allosteric potentiators of metabotropic glutamate receptor 2 (mGluR2): efficacy in an animal model for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology and functions of metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of dizocilpine-induced disruption of prepulse inhibition of an acoustic startle response by the 5-HT2 receptor antagonist ketanserin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-007-0974-X

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18057917

ResearchGate publication ID

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