(Q46882307)

English

Virtual screening and experimental verification to identify potential inhibitors of the ErmC methyltransferase responsible for bacterial resistance against macrolide antibiotics

scientific article published in February 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

Virtual screening and experimental verification to identify potential inhibitors of the ErmC methyltransferase responsible for bacterial resistance against macrolide antibiotics (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

virtual screening

1 reference

based on heuristic

inferred from title

Janusz Bujnicki

6

object named as

Janusz M Bujnicki

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

2

object named as

Elzbieta Purta

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

author name string

Marcin Feder

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

Lukasz Koscinski

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

Sonja Cubrilo

4

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

Gordana Maravic Vlahovicek

5

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

publication date

1 February 2008

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

2

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

316-322

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

Erythromycin resistance by ribosome modification

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

21 January 2018

Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

21 January 2018

The bacterial ribosome as a target for antibiotics

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Evolution and global dissemination of macrolide-resistant group A streptococci

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Ketolide resistance in Streptococcus pyogenes correlates with the degree of rRNA dimethylation by Erm.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Assays to detect and characterize synthetic agents that inhibit the ErmC methyltransferase.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Similarity based virtual screening: a tool for targeted library design

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutational analysis defines the roles of conserved amino acid residues in the predicted catalytic pocket of the rRNA:m6A methyltransferase ErmC'.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutational analysis of basic residues in the N-terminus of the rRNA:m6A methyltransferase ErmC'.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis of intrinsic macrolide resistance in the Mycobacterium tuberculosis complex

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Methyltransferase Erm(37) slips on rRNA to confer atypical resistance in Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

AdoMet-dependent methylation, DNA methyltransferases and base flipping

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Natural history of S-adenosylmethionine-binding proteins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

A graph-theory algorithm for rapid protein side-chain prediction

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

CHARMM fluctuating charge force field for proteins: II protein/solvent properties from molecular dynamics simulations using a nonadditive electrostatic model.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Surflex: fully automatic flexible molecular docking using a molecular similarity-based search engine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Further development and validation of empirical scoring functions for structure-based binding affinity prediction

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700201

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/CMDC.200700201

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18038381

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