(Q46885841)

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4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG.

scientific article published on 23 November 2007

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18034189%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG (English)

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27 December 2019

4

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27 December 2019

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27 December 2019

Klaus-Michael Debatin

10

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27 December 2019

Mike-Andrew Westhoff

2

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27 December 2019

Pamela Fischer-Posovszky

3

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27 December 2019

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Strauss G

1

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27 December 2019

Schanbacher M

5

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27 December 2019

Eckhoff SM

6

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27 December 2019

Stahnke K

7

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27 December 2019

Vahsen N

8

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27 December 2019

publication date

23 November 2007

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27 December 2019

Cell Death & Differentiation

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27 December 2019

15

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27 December 2019

2

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27 December 2019

332-343

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27 December 2019

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

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Oxidative DNA damage induced by a hydroperoxide derivative of cyclophosphamide

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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Alkylating DNA damage stimulates a regulated form of necrotic cell death

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Cytochrome c is released from mitochondria in a reactive oxygen species (ROS)-dependent fashion and can operate as a ROS scavenger and as a respiratory substrate in cerebellar neurons undergoing excitotoxic death

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Involvement of endonuclease G in nucleosomal DNA fragmentation under sustained endogenous oxidative stress

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

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Cytochrome c release from mitochondria of early postimplantation murine embryos exposed to 4-hydroperoxycyclophosphamide, heat shock, and staurosporine

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Role of caspases in murine limb bud cell death induced by 4-hydroperoxycyclophosphamide, an activated analog of cyclophosphamide

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10.1038/SJ.CDD.4402272

1 reference

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27 December 2019

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27 December 2019

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