(Q46888544)

26 December 2017

title

VSG-GPI anchors of African trypanosomes: their role in macrophage activation and induction of infection-associated immunopathology (English)

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26 December 2017

author

Benoît Stijlemans

2

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26 December 2017

Stefan Magez

object named as

Stefan Magez

1

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author name string

Toya Baral

3

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26 December 2017

Patrick De Baetselier

4

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26 December 2017

publication date

1 July 2002

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26 December 2017

published in

Microbes and Infection

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26 December 2017

volume

4

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26 December 2017

issue

9

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26 December 2017

page(s)

999-1006

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26 December 2017

Genetic controls for the expression of surface antigens in African trypanosomes

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Trypanosoma brucei variable surface antigen is released by degenerating parasites but not by actively dividing parasites

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Correlation of high serum levels of tumor necrosis factor-alpha with disease severity in human African trypanosomiasis

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A role for TNF during African trypanosomiasis: involvement in parasite control, immunosuppression and pathology

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Immunopathology of experimental African sleeping sickness: detection of cytokine mRNA in the brains of Trypanosoma brucei brucei-infected mice

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7 January 2021

The membrane form of variant surface glycoproteins of Trypanosoma brucei

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7 January 2021

Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membrane

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7 January 2021

Characterisation of the asparagine-linked oligosaccharides from Trypanosoma brucei type-I variant surface glycoproteins

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Glycosyl-phosphatidylinositol molecules of the parasite and the host

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7 January 2021

Characterization of the cross-reacting determinant (CRD) of the glycosyl-phosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoprotein

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7 January 2021

The lumen of the flagellar pocket of Trypanosoma brucei contains both intact and phospholipase C-cleaved GPI anchored proteins

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Simultaneous but independent activation of adenylate cyclase and glycosylphosphatidylinositol-phospholipase C under stress conditions in Trypanosoma brucei

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7 January 2021

The GPI-phospholipase C of Trypanosoma brucei is nonessential but influences parasitemia in mice.

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Virulence of Trypanosoma brucei strain 427 is not affected by the absence of glycosylphosphatidylinositol phospholipase C.

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7 January 2021

Attenuation of Trypanosoma brucei is associated with reduced immunosuppression and concomitant production of Th2 lymphokines

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Interleukin-4-dependent immunoglobulin G1 isotype switch in the presence of a polarized antigen-specific Th1-cell response to the trypanosome variant surface glycoprotein.

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7 January 2021

Murine tumour necrosis factor plays a protective role during the initial phase of the experimental infection with Trypanosoma brucei brucei.

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7 January 2021

Detoxified exoantigens and phosphatidylinositol derivatives inhibit tumor necrosis factor induction by malarial exoantigens

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7 January 2021

Glycosylphosphatidylinositol toxin of Trypanosoma brucei regulates IL-1 alpha and TNF-alpha expression in macrophages by protein tyrosine kinase mediated signal transduction.

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7 January 2021

Endotoxins and their significance for murine trypanosomiasis

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7 January 2021

An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the stimulation of bovine monocytes

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7 January 2021

Specificity in signal transduction among glycosylphosphatidylinositols of Plasmodium falciparum, Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp.

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7 January 2021

Highly purified glycosylphosphatidylinositols from Trypanosoma cruzi are potent proinflammatory agents

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7 January 2021

Plasmodium falciparum glycosylphosphatidylinositol-induced TNF-alpha secretion by macrophages is mediated without membrane insertion or endocytosis

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7 January 2021

Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite

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7 January 2021

Phospholipid-containing toxic malaria antigens induce hypoglycaemia

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7 January 2021

Human and murine macrophages produce TNF in response to soluble antigens of Plasmodium falciparum

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7 January 2021

A monoclonal antibody that recognizes phosphatidylinositol inhibits induction of tumor necrosis factor alpha by different strains of Plasmodium falciparum.

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7 January 2021

Inhibitory immunoglobulin M antibodies to tumor necrosis factor-inducing toxins in patients with malaria

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7 January 2021

Glycosylphosphatidylinositol anchors of Plasmodium falciparum: molecular characterization and naturally elicited antibody response that may provide immunity to malaria pathogenesis

1 reference

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7 January 2021

10.1016/S1286-4579(02)01617-9

Identifiers

DOI

1 reference

26 December 2017

1 reference

26 December 2017