(Q46891012)

English

Enforced epithelial expression of IGF-1 causes hyperplastic prostate growth while negative selection is requisite for spontaneous metastogenesis

scientific article published on 19 November 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

Enforced epithelial expression of IGF-1 causes hyperplastic prostate growth while negative selection is requisite for spontaneous metastogenesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

author name string

Kaplan-Lefko PJ

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

Sutherland BW

2

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

Evangelou AI

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

Hadsell DL

4

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

Barrios RJ

5

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

Foster BA

6

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

Demayo F

7

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

Greenberg NM

8

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

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publication date

19 November 2007

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

27

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

20

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

2868-2876

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210943

0 references

IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro.

1 reference

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Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue.

1 reference

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Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor

1 reference

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Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study

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Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer.

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Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

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Tyrosine kinases expressed in vivo by human prostate cancer bone marrow metastases and loss of the type 1 insulin-like growth factor receptor

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Transcriptional regulation of insulin-like growth factor-I receptor gene expression in prostate cancer cells

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Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice

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Steroid hormones, polypeptide growth factors, hormone refractory prostate cancer, and the neuroendocrine phenotype

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Increased levels of urokinase plasminogen activator receptor in prostate cancer cells derived from repeated metastasis

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Insulin-like growth factor ligands, receptors, and binding proteins in cancer.

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Prostate cancer in a transgenic mouse

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The rat probasin gene promoter directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice.

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Epithelial stem cells in human prostate growth and disease

1 reference

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Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells

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Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression

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The insulin-like growth factor system

1 reference

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21 January 2018

The insulin-like growth factor system and cancer

1 reference

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21 January 2018

Tumour suppressor genes in prostate cancer.

1 reference

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21 January 2018

Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer

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21 January 2018

Characterization of the affinities of insulin-like growth factor (IGF)-binding proteins 1-4 for IGF-I, IGF-II, IGF-I/insulin hybrid, and IGF-I analogs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210943

21 January 2018

Androgen receptor (AR) expression in AR-negative prostate cancer cells results in differential effects of DHT and IGF-I on proliferation and AR activity between localized and metastatic tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210943

21 January 2018

Insulin-like growth factors and neoplasia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210943

21 January 2018

IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation

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21 January 2018

Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis

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21 January 2018

Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.

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21 January 2018

Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210943

21 January 2018

The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis

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21 January 2018

Peptide growth factors in the prostate as mediators of stromal epithelial interaction.

1 reference

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7 January 2021

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Effect of growth hormone (GH) and insulin-like growth factor I on prostate diseases: an ultrasonographic and endocrine study in acromegaly, GH deficiency, and healthy subjects

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Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression

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Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis

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Pathobiology of autochthonous prostate cancer in a pre‐clinical transgenic mouse model

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A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model

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Low levels of insulin-like growth factor type 1 receptor expression at cancer cell membrane predict liver metastasis in Dukes' C human colorectal cancers

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Plasma insulin-like growth factor-1 and binding protein-3 and subsequent risk of prostate cancer in the PSA era

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Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer

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Hormonal predictors of prostate cancer: a meta-analysis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210943

7 January 2021

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Transgenic mice overexpressing the prolactin gene develop dramatic enlargement of the prostate gland

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Clinical relevance of systemic and local IGF-I.

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Identifiers

10.1038/SJ.ONC.1210943

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/18026134

ResearchGate publication ID

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