(Q46894958)

26 December 2017

title

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer (English)

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26 December 2017

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10

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26 December 2017

Aaron Pollett

11

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26 December 2017

John McPherson

13

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26 December 2017

Charles G. Mullighan

14

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26 December 2017

Catherine A O'Brien

Catherine A O'Brien

2

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John Dick

John E Dick

16

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Steven Gallinger

12

Steven Gallinger

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26 December 2017

Faiyaz Notta

5

Faiyaz Notta

1 reference

26 December 2017

Peter van Galen

3

Peter van Galen

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26 December 2017

Antonija Kreso

1

Antonija Kreso

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26 December 2017

Erno Wienholds

9

Erno Wienholds

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26 December 2017

Olga I Gan

4

Olga I Gan

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26 December 2017

author name string

Andrew M K Brown

6

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26 December 2017

Karen Ng

7

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26 December 2017

Jing Ma

8

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26 December 2017

Darryl Shibata

15

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26 December 2017

language of work or name

English

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publication date

13 December 2012

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26 December 2017

published in

Science

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26 December 2017

volume

339

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26 December 2017

issue

6119

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26 December 2017

page(s)

543-548

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26 December 2017

Clonal evolution in cancer

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The life history of 21 breast cancers

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 January 2018

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Genetic variegation of clonal architecture and propagating cells in leukaemia

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Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.

21 January 2018

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Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

21 January 2018

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Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

21 January 2018

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Clonal selection drives genetic divergence of metastatic medulloblastoma

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

21 January 2018

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A mutation conferring resistance to imatinib at the time of diagnosis of chronic myelogenous leukemia.

21 January 2018

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Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment?

21 January 2018

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Rac activation and inactivation control plasticity of tumor cell movement

21 January 2018

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Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

21 January 2018

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A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

21 January 2018

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A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells

21 January 2018

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Tumor-initiating cells are rare in many human tumors

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Comparative lesion sequencing provides insights into tumor evolution

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Intra-tumour heterogeneity: a looking glass for cancer?

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Stochasticity in gene expression: from theories to phenotypes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Biodiversity and ecosystem functioning: current knowledge and future challenges

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Functional and phylogenetic diversity as predictors of biodiversity--ecosystem-function relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Noise minimization in eukaryotic gene expression

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

A yeast prion provides a mechanism for genetic variation and phenotypic diversity

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Control of stochasticity in eukaryotic gene expression

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Persister cells, dormancy and infectious disease

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Local recurrence of colorectal cancer: the problem, mechanisms, management and adjuvant therapy

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Noise in gene expression: origins, consequences, and control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Reference alignment of SNP microarray signals for copy number analysis of tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Circular binary segmentation for the analysis of array-based DNA copy number data

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Microdroplet-based PCR enrichment for large-scale targeted sequencing

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

A framework for variation discovery and genotyping using next-generation DNA sequencing data

21 January 2018

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ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

High DNA methylation pattern intratumoral diversity implies weak selection in many human colorectal cancers

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites

21 January 2018

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Comprehensive molecular characterization of human colon and rectal cancer

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Inferring human stem cell behaviour from epigenetic drift

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Developmental potential and dynamic behavior of hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Stem cell concepts renew cancer research

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Identification and expansion of human colon-cancer-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Phenotypic characterization of human colorectal cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

CD133+CD44+ population efficiently enriches colon cancer initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Characterization of a subpopulation of colon cancer cells with stem cell-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

ID1 and ID3 regulate the self-renewal capacity of human colon cancer-initiating cells through p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1227670

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1227670

1 reference

26 December 2017

ADS bibcode

2013Sci...339..543K

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1 reference

26 December 2017