(Q46924515)

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Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice

scientific article published on 25 July 2014

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

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Dewei Ye

1

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Yudong Wang

2

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Huating Li

3

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Weiping Jia

4

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Kwan Man

5

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Chung Mau Lo

6

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Yu Wang

7

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Karen S L Lam

8

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Aimin Xu

9

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

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25 July 2014

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Europe PubMed Central

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26 December 2017

http://europepmc.org/abstract/MED/24590984

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

60

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

3

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

977-989

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

Acute liver failure

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Current issues with acetaminophen hepatotoxicity--a clinically relevant model to test the efficacy of natural products

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Fibroblast growth factor 21: from pharmacology to physiology

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

FGF-21 as a novel metabolic regulator

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Inhibition of growth hormone signaling by the fasting-induced hormone FGF21.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Transcribe to survive: transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

p53 orchestrates the PGC-1α-mediated antioxidant response upon mild redox and metabolic imbalance

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Involvement of mitochondrial permeability transition in acetaminophen-induced liver injury in mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

The cytoprotective role of the Keap1-Nrf2 pathway

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

PGC-1 coactivators in the control of energy metabolism

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

Punctum on two different transcription factors regulated by PGC-1α: nuclear factor erythroid-derived 2-like 2 and nuclear respiratory factor 2.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

21 January 2018

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct changes in serum fibroblast growth factor 21 levels in different subtypes of diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

7 January 2021

based on heuristic

inferred from DOI database lookup

Aldo-keto reductase-7A protects liver cells and tissues from acetaminophen-induced oxidative stress and hepatotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.27060

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/HEP.27060

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/24590984

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