(Q46927614)

English

PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation

scientific article published on 26 October 2007

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scholarly article

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation (English)

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

pulmonary fibrosis

1 reference

based on heuristic

inferred from title

pulmonary hypertension

1 reference

based on heuristic

inferred from title

author name string

Anna R Hemnes

1

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

Ari Zaiman

2

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

Hunter C Champion

3

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

publication date

26 October 2007

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

American Journal of Physiology - Lung Cellular and Molecular Physiology

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

294

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

1

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

L24-33

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

The Rac and Rho hall of fame: a decade of hypertrophic signaling hits

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses.

1 reference

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21 January 2018

Pulmonary fibrosis: searching for model answers

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Sildenafil improves walk distance in idiopathic pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: a new action for an old drug?

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Sildenafil citrate therapy for pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Gene transfer of vascular endothelial growth factor reduces bleomycin-induced pulmonary hypertension in immature rabbits.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

NAD(P)H oxidase: role in cardiovascular biology and disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Redox-active protein thioredoxin prevents proinflammatory cytokine- or bleomycin-induced lung injury.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Beneficial acute effects of rho-kinase inhibitor in patients with pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric oxide synthase in a murine model of viral myocarditis

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Pressure-induced matrix metalloproteinase-9 contributes to early hypertensive remodeling.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Activation of NADPH oxidase during progression of cardiac hypertrophy to failure

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

C-type natriuretic peptide attenuates bleomycin-induced pulmonary fibrosis in mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Enalapril protects mice from pulmonary hypertension by inhibiting TNF-mediated activation of NF-kappaB and AP-1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Sildenafil prevents change in RhoA expression induced by chronic hypoxia in rat pulmonary artery.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Reactive oxygen species as mediators of calcium signaling by angiotensin II: implications in vascular physiology and pathophysiology

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Haemodynamic sequelae of pulmonary fibrosis following intratracheal bleomycin in rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Rac and Rho play opposing roles in the regulation of hypoxia/reoxygenation-induced permeability changes in pulmonary artery endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Clinical and laboratory features of scleroderma patients with pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00245.2007

21 January 2018

Identifiers

10.1152/AJPLUNG.00245.2007

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

release_66qxojjyljfblehadobx3jwyhm

1 reference

https://api.fatcat.wiki/v0/release/66qxojjyljfblehadobx3jwyhm

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17965319

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