(Q46950668)

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Differential involvement of reactive oxygen species in apoptosis caused by the inhibition of protein phosphatase 2A in Jurkat and CCRF-CEM human T-leukemia cells

scientific article published on 2 October 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

Differential involvement of reactive oxygen species in apoptosis caused by the inhibition of protein phosphatase 2A in Jurkat and CCRF-CEM human T-leukemia cells (English)

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

reactive oxygen species

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based on heuristic

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author name string

Robert T M Boudreau

1

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

David M Conrad

2

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

David W Hoskin

3

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

publication date

2 October 2007

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

Experimental and Molecular Pathology

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

83

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

3

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

347-356

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress

1 reference

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Biochemical pathways of caspase activation during apoptosis

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Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss

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Signalling apoptosis: a radical approach.

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Inhibitors of protein phosphatases 1 and 2A differentially prevent intrinsic and extrinsic apoptosis pathways

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Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex

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Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A

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Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid, and tautomycin

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Okadaic acid, useful tool for studying cellular processes

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Mitochondrial reactive oxygen species in cell death signaling

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Compartment-dependent management of H(2)O(2) by peroxisomes.

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Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis

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Reactive oxygen species in living systems: source, biochemistry, and role in human disease

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Type-2A protein phosphatase activity is required to maintain death receptor responsiveness.

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Glutathione depletion-induced chromosomal DNA fragmentation associated with apoptosis and necrosis.

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Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acid

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Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

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A rapid method for the isolation of functional thymus-derived murine lymphocytes

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.

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Nuclear apoptotic changes: an overview

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The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins

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The JAM test. A simple assay for DNA fragmentation and cell death

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The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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Physiologic importance of protein phosphatase inhibitors

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ROS stress in cancer cells and therapeutic implications

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Simultaneous flow cytometric method to measure phagocytosis and oxidative products by neutrophils

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Mechanisms of cell death in oxidative stress

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Involvement of protein phosphatase 2A in interferon-alpha-2b-induced apoptosis in K562 human chronic myelogenous leukaemia cells.

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Role of serine/threonine protein phosphatase 2A in cancer

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Dephosphorylation of Bcl-2 by protein phosphatase 2A results in apoptosis resistance

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A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle

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A flow-cytometric method for the separation and quantitation of normal and apoptotic thymocytes

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A cellular poison cupboard

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Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells.

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Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria

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Generation of hydrogen peroxide precedes loss of mitochondrial membrane potential during DNA alkylation-induced apoptosis

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Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells

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Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation

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Identifiers

10.1016/J.YEXMP.2007.09.003

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17936751

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