(Q46952807)

26 December 2017

title

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury (English)

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26 December 2017

author

Kenneth K. Teng

4

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26 December 2017

Michael Gotthardt

8

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26 December 2017

Gary Lewin

12

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26 December 2017

Anders Nykjaer

15

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26 December 2017

Tilman Breiderhoff

object named as

Tilman Breiderhoff

7

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Thomas E Willnow

object named as

Thomas E Willnow

14

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author name string

Pernille Jansen

1

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26 December 2017

Klaus Giehl

2

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26 December 2017

Jens R Nyengaard

3

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26 December 2017

Oleg Lioubinski

5

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26 December 2017

Susanne S Sjoegaard

6

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26 December 2017

Fuyu Lin

9

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26 December 2017

Andreas Eilers

10

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26 December 2017

Claus M Petersen

11

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26 December 2017

Barbara L Hempstead

13

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26 December 2017

language of work or name

English

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publication date

14 October 2007

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26 December 2017

published in

Nature Neuroscience

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26 December 2017

volume

10

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26 December 2017

page(s)

1449-1457

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26 December 2017

issue

11

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26 December 2017

https://scigraph.springernature.com/pub.10.1038/nn2000

exact match

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cites work

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease.

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Neurotrophins and their receptors: a convergence point for many signalling pathways

21 January 2018

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7 January 2021

p75NTR--live or let die.

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7 January 2021

The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo

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7 January 2021

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

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7 January 2021

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

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7 January 2021

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

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7 January 2021

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

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7 January 2021

Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons

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7 January 2021

Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival.

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7 January 2021

Regulation of cell survival by secreted proneurotrophins

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7 January 2021

Sortilin is essential for proNGF-induced neuronal cell death

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7 January 2021

ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

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7 January 2021

Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins.

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7 January 2021

Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade

1 reference

7 January 2021

Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons.

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7 January 2021

Pro-NGF secreted by astrocytes promotes motor neuron cell death

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7 January 2021

The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death

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7 January 2021

Neurotrophin receptor interacting factor (NRIF) is an essential mediator of apoptotic signaling by the p75 neurotrophin receptor

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7 January 2021

Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis.

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7 January 2021

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

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7 January 2021

Increased pro-nerve growth factor and p75 neurotrophin receptor levels in developing hypothyroid rat cerebral cortex are associated with enhanced apoptosis.

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7 January 2021

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

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7 January 2021

Induction of apoptosis by the low-affinity NGF receptor

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7 January 2021

TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal

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7 January 2021

Nerve growth factor enhances the dendritic arborization of sympathetic ganglion cells undergoing atrophy in aged rats.

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7 January 2021

The role of NGF uptake in selective vulnerability to cell death in ageing sympathetic neurons.

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7 January 2021

Pathologic alterations in pre- and postsynaptic elements in aged mouse sympathetic ganglia

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7 January 2021

Heterogeneous requirement of NGF for sympathetic target innervation in vivo

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7 January 2021

Dependence on p75 for innervation of some sympathetic targets.

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7 January 2021

Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development.

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7 January 2021

Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye.

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7 January 2021

Microglia-Derived Nerve Growth Factor Causes Cell Death in the Developing Retina

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7 January 2021

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

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7 January 2021

Neurotrophins: roles in neuronal development and function

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7 January 2021

Growth and survival signals controlling sympathetic nervous system development

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7 January 2021

Nerve growth factor (NGF), proNGF and NGF receptor-like immunoreactivity in BB rat retina.

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7 January 2021

Increased NGF proforms in aged sympathetic neurons and their targets

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7 January 2021

Sympathetic neurons synthesize and secrete pro-nerve growth factor protein

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7 January 2021

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

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7 January 2021

An axotomy model for the induction of death of rat and mouse corticospinal neurons in vivo.

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7 January 2021

BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo

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7 January 2021

Endogenous brain-derived neurotrophic factor and neurotrophin-3 antagonistically regulate survival of axotomized corticospinal neurons in vivo

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7 January 2021

Tissue shrinkage and unbiased stereological estimation of particle number and size

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7 January 2021

Identifiers

DOI

10.1038/NN2000

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26 December 2017

Dimensions Publication ID

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26 December 2017