(Q46959089)

26 December 2017

title

Zonal gene expression in murine liver: lessons from tumors (English)

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26 December 2017

author name string

Stephan Hailfinger

1

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26 December 2017

Maike Jaworski

2

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26 December 2017

Albert Braeuning

3

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26 December 2017

Albrecht Buchmann

4

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26 December 2017

Michael Schwarz

5

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26 December 2017

language of work or name

English

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publication date

1 March 2006

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26 December 2017

published in

Hepatology

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26 December 2017

volume

43

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26 December 2017

issue

3

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26 December 2017

page(s)

407-414

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26 December 2017

Evidence that interaction of hepatocytes with the collecting (hepatic) veins triggers position-specific transcription of the glutamine synthetase and ornithine aminotransferase genes in the mouse liver

cites work

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Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

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Glucagon regulation of gluconeogenesis and ketogenesis in periportal and perivenous rat hepatocytes. Heterogeneity of hormone action and of the mitochondrial redox state

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Functional specialization of different hepatocyte populations

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7 January 2021

Metabolic zonation of the liver: regulation and implications for liver function

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7 January 2021

Zonation of metabolism and gene expression in liver.

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7 January 2021

A mechanistic model for the development and maintenance of portocentral gradients in gene expression in the liver

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7 January 2021

Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture.

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7 January 2021

Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isoenzymes, NADPH P450-reductase, glutathione transferases and microsomal epoxide hydrolase.

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7 January 2021

Polychlorinated biphenyls, classified as either phenobarbital- or 3-methylcholanthrene-type inducers of cytochrome P-450, are both hepatic tumor promoters in diethylnitrosamine-initiated rats.

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7 January 2021

Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors

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7 January 2021

A beta-catenin-dependent pathway regulates expression of cytochrome P450 isoforms in mouse liver tumors

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7 January 2021

Genotype-phenotype relationships in hepatocellular tumors from mice and man.

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7 January 2021

Human p53 knock-in (hupki) mice do not differ in liver tumor response from their counterparts with murine p53.

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7 January 2021

Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis

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7 January 2021

New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism

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7 January 2021

Development of the ornithine cycle in rat liver: zonation of a metabolic pathway

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7 January 2021

Colocalization in pericentral hepatocytes in adult mice and similarity in developmental expression pattern of ornithine aminotransferase and glutamine synthetase mRNA

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7 January 2021

Expression of catenins during mouse embryonic development and in adult tissues

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7 January 2021

Beta-catenin: a key mediator of Wnt signaling

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7 January 2021

The Wnt signaling pathway and its role in tumor development

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7 January 2021

Links between signal transduction, transcription and adhesion in epithelial bud development

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7 January 2021

The spontaneous induction of glutamine synthetase in pig hepatocytes cocultured with RL-ET-14 cells is completely inhibited by trijodothyronine and okadaic acid

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7 January 2021

The RL-ET-14 cell line mediates expression of glutamine synthetase through the upstream enhancer/promoter region.

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7 January 2021

B-raf and Ha-ras mutations in chemically induced mouse liver tumors

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7 January 2021

Downregulation of aryl hydrocarbon receptor function and cytochrome P450 1A1 induction by expression of Ha-ras oncogenes

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7 January 2021

Regulation of cytochrome P-450 CYPIA1 gene expression and proto-oncogene expression by growth factors in primary hepatocytes

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7 January 2021

Induction of cytochrome P450 2B1 by pyrethroids in primary rat hepatocyte cultures

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7 January 2021

An intronic silencer element is responsible for specific zonal expression of glutamine synthetase in the rat liver

1 reference

7 January 2021

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

7 January 2021

Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation

1 reference

7 January 2021

Experimental evidence that the physiological position of the liver within the circulation is not a major determinant of zonation of gene expression

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7 January 2021

Identifiers

DOI

10.1002/HEP.21082

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26 December 2017

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26 December 2017