(Q46960831)

26 December 2017

title

hTERT, the catalytic component of telomerase, is downregulated in the haematopoietic stem cells of patients with chronic myeloid leukaemia (English)

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26 December 2017

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9

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26 December 2017

author name string

Campbell LJ

1

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26 December 2017

Fidler C

2

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26 December 2017

Eagleton H

3

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26 December 2017

Peniket A

4

1 reference

26 December 2017

Kusec R

5

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26 December 2017

Gal S

6

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26 December 2017

Littlewood TJ

7

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26 December 2017

Wainscoat JS

8

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26 December 2017

publication date

1 April 2006

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26 December 2017

published in

Leukemia

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26 December 2017

volume

20

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26 December 2017

issue

4

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26 December 2017

page(s)

671-679

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26 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404141

exact match

0 references

cites work

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The biology of CML blast crisis

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Structure and function of telomeres

21 January 2018

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A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

21 January 2018

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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

21 January 2018

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The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

21 January 2018

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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Telomeres shorten during ageing of human fibroblasts

21 January 2018

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Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

21 January 2018

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Regulation of telomerase by telomeric proteins

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The RNA component of human telomerase

21 January 2018

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Telomerase catalytic subunit homologs from fission yeast and human

21 January 2018

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A mammalian telomerase-associated protein

21 January 2018

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Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT)

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Telomerase regulation: not just flipping the switch

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Direct activation of TERT transcription by c-MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

21 January 2018

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The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor

21 January 2018

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Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

21 January 2018

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Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

21 January 2018

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21 January 2018

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TRF2 Protects Human Telomeres from End-to-End Fusions

21 January 2018

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A survey of telomerase activity in human cancer

21 January 2018

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Telomere reduction in human colorectal carcinoma and with ageing

21 January 2018

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Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma

21 January 2018

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A critical role for telomeres in suppressing and facilitating carcinogenesis

21 January 2018

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Telomere length shortening is associated with disease evolution in chronic myelogenous leukemia.

21 January 2018

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Different expression levels of the telomerase catalytic subunit hTERT in myeloproliferative and myelodysplastic diseases

21 January 2018

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Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression.

21 January 2018

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Increased telomerase activity is associated with shorter survival in patients with chronic phase chronic myeloid leukemia

21 January 2018

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Dysregulated expression of the major telomerase components in leukaemic stem cells.

21 January 2018

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The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity

21 January 2018

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Telomerase activity in normal and malignant hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Telomerase activity in human leukemic cell lines is inhibited by antisense pentadecadeoxynucleotides targeted against c-myc mRNA.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Control of telomere length by the human telomeric protein TRF1

21 January 2018

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Senescence Induced by Altered Telomere State, Not Telomere Loss

21 January 2018

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Normalization of previously shortened telomere length under treatment with imatinib argues against a preexisting telomere length deficit in normal hematopoietic stem cells from patients with chronic myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Gene expression profiling of Philadelphia chromosome (Ph)-negative CD34+ hematopoietic stem and progenitor cells of patients with Ph-positive CML in major molecular remission during therapy with imatinib

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Telomerase activity in B-cell non-Hodgkin lymphomas is regulated by hTERT transcription and correlated with telomere-binding protein expression but uncoupled from proliferation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Tankyrase promotes telomere elongation in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Dynamics of telomere erosion and its association with genome instability in myelodysplastic syndromes (MDS) and acute myelogenous leukemia arising from MDS: a marker of disease prognosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

Telomerase activity and the expression of telomerase components in acute myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

inferred from DOI database lookup

7 January 2021

based on heuristic

Correlation of the expression of human telomerase subunits with telomerase activity in normal skin and skin tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

inferred from DOI database lookup

7 January 2021

based on heuristic

The correlation of TERT expression with c-myc expression in cervical cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404141

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.LEU.2404141

1 reference

26 December 2017

1 reference

26 December 2017