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The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor
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title
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor
(English)
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main subject
Telomerase reverse transcriptase
1 reference
stated in
GOA release 2020-03-11
PIN2 (TERF1) interacting telomerase inhibitor 1
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stated in
GOA release 2020-03-11
negative regulation of telomerase activity
1 reference
stated in
GOA release 2020-03-11
PIN2/TERF1 interacting, telomerase inhibitor 1
1 reference
stated in
GOA release 2020-03-11
author name string
X Z Zhou
series ordinal
1
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K P Lu
series ordinal
2
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language of work or name
English
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publication date
2 November 2001
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published in
Cell
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volume
107
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issue
3
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page(s)
347-59
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cites work
G-patch: a new conserved domain in eukaryotic RNA-processing proteins and type D retroviral polyproteins
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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inferred from DOI database lookup
A critical role for telomeres in suppressing and facilitating carcinogenesis
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
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inferred from DOI database lookup
TRF1 is a dimer and bends telomeric DNA
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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Association of 8p23 Deletions with Poor Survival in Head and Neck Cancer
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reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of life-span by introduction of telomerase into normal human cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
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inferred from DOI database lookup
Telomerase activity in normal and malignant hematopoietic cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
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inferred from DOI database lookup
Telomere elongation in immortal human cells without detectable telomerase activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human telomeric protein
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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inferred from DOI database lookup
Variability at the telomeres of the human X/Y pseudoautosomal region
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
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inferred from DOI database lookup
Regulation of telomere length and function by a Myb-domain protein in fission yeast
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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inferred from DOI database lookup
The catalytic subunit of yeast telomerase
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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A physical map of 30,000 human genes
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reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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inferred from DOI database lookup
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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Est1 and Cdc13 as comediators of telomerase access
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reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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The RNA component of human telomerase
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reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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SV40-INDUCED TRANSFORMATION OF HUMAN DIPLOID CELLS: CRISIS AND RECOVERY
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reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
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inferred from DOI database lookup
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Creation of human tumour cells with defined genetic elements
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of telomerase limits the growth of human cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase activity is sufficient to allow transformed cells to escape from crisis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomeres shorten during ageing of human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere reduction in human colorectal carcinoma and with ageing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The serial cultivation of human diploid cell strains
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reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent allelic loss and homozygous deletion in chromosome band 8p23 in oral cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase activation by the E6 gene product of human papillomavirus type 16.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of mouse telomerase in highly proliferative organs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reverse transcriptase motifs in the catalytic subunit of telomerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a NIMA-like mitotic pathway in vertebrate cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human peptidyl-prolyl isomerase essential for regulation of mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Function of WW domains as phosphoserine- or phosphothreonine-binding modules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomeres and their control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High density deletion mapping of bladder cancer localizes the putative tumor suppressor gene between loci D8S504 and D8S264 at chromosome 8p23.3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase catalytic subunit homologs from fission yeast and human
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A specific interaction between the telomeric protein Pin2/TRF1 and the mitotic spindle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of nucleoside diphosphate kinase nm23-H2 with human telomeres
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomeres and telomerase: implications for cancer and aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase and human tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletions define a region of 8p23.2 containing a putative tumor suppressor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of telomerase activity in malignant and nonmalignant skin conditions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of telomere length by the human telomeric protein TRF1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc activates telomerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct activation of TERT transcription by c-MYC.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Organization and expression of human telomere repeat binding factor genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pif1p helicase, a catalytic inhibitor of telomerase in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(01)00538-4
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3529645
OpenCitations bibliographic resource ID
3529645
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3529645
PubMed ID
11701125
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3529645
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