(Q46963474)

English

Glutathione and the redox control system trypanothione/trypanothione reductase are involved in the protection of Leishmania spp. against nitrosothiol-induced cytotoxicity

scientific article published on 22 February 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

Glutathione and the redox control system trypanothione/trypanothione reductase are involved in the protection of Leishmania spp. against nitrosothiol-induced cytotoxicity (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

0 references

object named as

Leishmania

1 reference

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author name string

P R T Romão

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

J Tovar

2

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

S G Fonseca

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

R H Moraes

4

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

A K Cruz

5

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

J S Hothersall

6

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

A A Noronha-Dutra

7

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

S H Ferreira

8

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

F Q Cunha

9

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

language of work or name

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publication date

22 February 2006

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

Brazilian Journal of Medical and Biological Research

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

39

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

355-363

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Metabolism and functions of trypanothione in the Kinetoplastida

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

A unique cascade of oxidoreductases catalyses trypanothione-mediated peroxide metabolism in Crithidia fasciculata

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Ovothiol and trypanothione as antioxidants in trypanosomatids

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Evidence that trypanothione reductase is an essential enzyme in Leishmania by targeted replacement of the tryA gene locus

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Extrachromosomal, homologous expression of trypanothione reductase and its complementary mRNA in Trypanosoma cruzi.

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Induction of nitric oxide synthesis in J774 cells lowers intracellular glutathione: effect of modulated glutathione redox status on nitric oxide synthase induction

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

The mechanism of transmembrane S-nitrosothiol transport

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages.

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Leishmania spp.: nitric oxide-mediated metabolic inhibition of promastigote and axenically grown amastigote forms.

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Reduced glutathione esters--antidotes to toxicity. Cytotoxicity induced by hydrogen peroxide, 1-chloro-2,4-dinitrobenzene, and menadione in murine P388D1 macrophages in vitro

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Spin trapping of glutathiyl and protein radicals produced from nitric oxide-derived oxidants

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

N-acetylcysteine amide, a novel cell-permeating thiol, restores cellular glutathione and protects human red blood cells from oxidative stress

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Inhibition of glutathione synthesis as a chemotherapeutic strategy for trypanosomiasis

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Role of peroxynitrite in macrophage microbicidal mechanisms in vivo revealed by protein nitration and hydroxylation

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Carbon dioxide stimulates the production of thiyl, sulfinyl, and disulfide radical anion from thiol oxidation by peroxynitrite

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Nitric oxide, oxidants, and protein tyrosine nitration

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

EPR detection of glutathionyl and protein-tyrosyl radicals during the interaction of peroxynitrite with macrophages (J774).

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Down-regulation of Leishmania donovani trypanothione reductase by heterologous expression of a trans-dominant mutant homologue: effect on parasite intracellular survival

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Phenotype of recombinant Leishmania donovani and Trypanosoma cruzi which over-express trypanothione reductase. Sensitivity towards agents that are thought to induce oxidative stress.

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

The metabolism of S-nitrosothiols in the trypanosomatids: the role of ovothiol A and trypanothione

1 reference

https://api.crossref.org/works/10.1590%2FS0100-879X2006000300006

21 January 2018

Identifiers

10.1590/S0100-879X2006000300006

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16501815

ResearchGate publication ID

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