(Q46963924)

English

Binding of gefitinib, an inhibitor of epidermal growth factor receptor-tyrosine kinase, to plasma proteins and blood cells: in vitro and in cancer patients

scientific article published in July 2006

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Statements

scholarly article

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

Binding of gefitinib, an inhibitor of epidermal growth factor receptor-tyrosine kinase, to plasma proteins and blood cells: in vitro and in cancer patients (English)

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

4

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

Sharyn D. Baker

object named as

Sharyn D Baker

5

0 references

author name string

Jing Li

1

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

Julie Brahmer

2

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

Wells Messersmith

3

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

publication date

1 July 2006

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

Investigational New Drugs

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

24

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

4

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

291-297

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

https://scigraph.springernature.com/pub.10.1007/s10637-006-5269-2

0 references

Plasma protein binding of quinine: binding to human serum albumin, alpha 1-acid glycoprotein and plasma from patients with malaria

1 reference

https://api.crossref.org/works/10.1007%2FS10637-006-5269-2

21 January 2018

Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unpredicted clinical pharmacology of UCN-01 caused by specific binding to human alpha1-acid glycoprotein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered pharmacokinetics of a novel anticancer drug, UCN-01, caused by specific high affinity binding to alpha1-acid glycoprotein in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic modeling of paclitaxel encapsulation in Cremophor EL micelles

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor mutations in non-small-cell lung cancer: implications for treatment and tumor biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug binding to human alpha-1-acid glycoprotein in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected].

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of a new vinca alkaloid derivative, S12363, to human plasma proteins and platelets. Usefulness of an erythrocyte partitioning technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha1 acid glycoprotein binds to imatinib (STI571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein binding of itraconazole and fluconazole in patients with cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific method for determination of gefitinib in human plasma, mouse plasma and tissues using high performance liquid chromatography coupled to tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The (ir)relevance of plasma protein binding of anticancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous analysis of docetaxel and the formulation vehicle polysorbate 80 in human plasma by liquid chromatography/tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of unbound docetaxel: role of polysorbate 80 and serum proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro binding and partitioning of irinotecan (CPT-11) and its metabolite, SN-38, in human blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The epidermal growth factor receptor and its inhibition in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of alpha1 acid glycoprotein in the in vivo resistance of human BCR-ABL(+) leukemic cells to the abl inhibitor STI571

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ZD1839 ('Iressa') as an anticancer agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of cosalane--a novel highly lipophilic anti-HIV agent--to albumin and glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors affecting cytochrome P-450 3A activity in cancer patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16502356

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10637-006-5269-2

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16502356

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