(Q47071433)

5 January 2018

title

Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain (English)

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5 January 2018

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GOA release 2020-03-11

author

Patrik Verstreken

5

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5 January 2018

Bassem Hassan

8

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5 January 2018

Joannella Morales

object named as

Joannella Morales

1

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F Rob Jackson

6

object named as

F Rob Jackson

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5 January 2018

author name string

P Robin Hiesinger

2

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5 January 2018

Andrew J Schroeder

3

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5 January 2018

Kazuhiko Kume

4

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5 January 2018

David L Nelson

7

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5 January 2018

language of work or name

English

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publication date

1 June 2002

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5 January 2018

published in

Neuron

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5 January 2018

volume

34

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5 January 2018

page(s)

961-972

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5 January 2018

issue

6

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5 January 2018

Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain.

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Localisation of a human homologue of the Drosophila mnb and rat Dyrk genes to chromosome 21q22.2

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

A point mutation in the FMR-1 gene associated with fragile X mental retardation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Expression of the period clock gene within different cell types in the brain of Drosophila adults and mosaic analysis of these cells' influence on circadian behavioral rhythms

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

A de novo deletion in FMR1 in a patient with developmental delay.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Ectopic expression of the neuropeptide pigment-dispersing factor alters behavioral rhythms in Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Tissue-specific expression of a FMR1/beta-galactosidase fusion gene in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Analysis of neocortex in three males with the fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Dendritic spine structural anomalies in fragile-X mental retardation syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Altered circadian pacemaker functions and cyclic AMP rhythms in the Drosophila learning mutant dunce

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Signal analysis of behavioral and molecular cycles

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Intragenic loss of function mutations demonstrate the primary role of FMR1 in fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

A deletion of 1.6 kb proximal to the CGG repeat of the FMR1 gene causes the clinical phenotype of the fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Fragile X syndrome is less common than previously estimated

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Abnormal development of dendritic spines in FMR1 knock-out mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Behavioural phenotypes.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Absence of expression of the FMR-1 gene in fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Adult fragile X syndrome. Clinico-neuropathologic findings.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Prevalence of fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Neural development: The semantics of axon guidance

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

The Fra(X) syndrome: neurological, electrophysiological, and neuropathological abnormalities.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2900731-6

7 January 2021

10.1016/S0896-6273(02)00731-6

Identifiers

DOI

1 reference

5 January 2018

PubMed ID

12086643

1 reference

5 January 2018