(Q47071676)

5 January 2018

title

Control of Dpp morphogen signalling by a secreted feedback regulator (English)

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5 January 2018

author

Markus Affolter

6

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5 January 2018

Lucy Patterson

object named as

Lucy Patterson

3

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Matthias Hammerschmidt

5

object named as

Matthias Hammerschmidt

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5 January 2018

author name string

Robin Vuilleumier

1

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5 January 2018

Alexander Springhorn

2

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5 January 2018

Stefanie Koidl

4

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5 January 2018

George Pyrowolakis

7

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5 January 2018

publication date

9 May 2010

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5 January 2018

published in

Nature Cell Biology

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5 January 2018

volume

12

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5 January 2018

issue

6

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5 January 2018

page(s)

611-617

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5 January 2018

https://scigraph.springernature.com/pub.10.1038/ncb2064

exact match

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cites work

Heparan sulfate proteoglycans at a glance.

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Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog

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Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways

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The ventral and posterior expression of the zebrafish homeobox gene eve1 is perturbed in dorsalized and mutant embryos

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Dpp-responsive silencers are bound by a trimeric Mad-Medea complex

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Direct and long-range action of a DPP morphogen gradient.

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Morphogen gradient formation and vesicular trafficking

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Dally regulates Dpp morphogen gradient formation in the Drosophila wing.

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Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4.

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Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome

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Specificity and versatility in tgf-beta signaling through Smads

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Negative feedback mechanisms and their roles during pattern formation

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Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface.

1 reference

12 December 2020

Understanding morphogen gradients: a problem of dispersion and containment

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Xenopus SMOC-1 Inhibits bone morphogenetic protein signaling downstream of receptor binding and is essential for postgastrulation development in Xenopus

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Functions of heparan sulfate proteoglycans in cell signaling during development

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Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm

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12 December 2020

brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes.

1 reference

12 December 2020

The Decapentaplegic morphogen gradient: from pattern formation to growth regulation

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Feedback control of intercellular signalling in development

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Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient.

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Tbx24, encoding a T-box protein, is mutated in the zebrafish somite-segmentation mutant fused somites.

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Tgf-beta superfamily signaling in embryonic development and homeostasis

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Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc.

1 reference

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The extracellular regulation of bone morphogenetic protein signaling

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Dpp gradient formation in the Drosophila wing imaginal disc

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A simple molecular complex mediates widespread BMP-induced repression during Drosophila development.

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Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker

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An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases

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12 December 2020

TGF-beta/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing.

1 reference

12 December 2020

Expression of two zebrafish orthodenticle-related genes in the embryonic brain.

1 reference

12 December 2020

Ventral expression of GATA-1 and GATA-2 in the Xenopus embryo defines induction of hematopoietic mesoderm

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Not just a sink: endosomes in control of signal transduction

1 reference

12 December 2020

Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing.

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12 December 2020

Multiplex detection of RNA expression in Drosophila embryos

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New Drosophila transgenic reporters: insulated P-element vectors expressing fast-maturing RFP.

1 reference

12 December 2020

A conserved activation element in BMP signaling during Drosophila development

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12 December 2020

The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation.

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12 December 2020

Hox control of morphogen mobility and organ development through regulation of glypican expression

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12 December 2020

Action range of BMP is defined by its N-terminal basic amino acid core

1 reference

12 December 2020

The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog

1 reference

12 December 2020

Wingless gradient formation in the Drosophila wing

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12 December 2020

Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs.

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12 December 2020

Daughters against dpp modulates dpp organizing activity in Drosophila wing development

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12 December 2020

Gradient formation of the TGF-beta homolog Dpp.

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12 December 2020

Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans.

1 reference

12 December 2020

Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteins.

1 reference

12 December 2020

Wing vein patterning in Drosophila and the analysis of intercellular signaling

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCB2064

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5 January 2018

PubMed ID

20453847

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5 January 2018