(Q47103949)

8 January 2018

title

Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer's disease drug candidates (English)

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8 January 2018

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Kin Yip Tam

3

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author name string

Wei Zhou

series ordinal

1

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8 January 2018

Xiaohui Hu

series ordinal

2

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8 January 2018

language of work or name

English

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publication date

27 November 2017

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8 January 2018

published in

Scientific Reports

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8 January 2018

volume

7

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8 January 2018

issue

1

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8 January 2018

page(s)

16368

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8 January 2018

Creative Commons Attribution 4.0 International

copyright license

start time

27 November 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/s41598-017-16635-4

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cites work

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Study on the main components interaction from Flos Lonicerae and Fructus Forsythiae and their dissolution in vitro and intestinal absorption in rats

23 May 2018

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Activity of P-Glycoprotein, a β-Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease.

23 May 2018

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Memory loss in Alzheimer's disease

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703966

Evidence for impaired amyloid β clearance in Alzheimer's disease

23 May 2018

1 reference

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Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?

23 May 2018

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Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease

23 May 2018

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Beta amyloid effects on expression of multidrug efflux transporters in brain endothelial cells

23 May 2018

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Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer's disease

23 May 2018

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Specific inhibitors of the breast cancer resistance protein (BCRP).

23 May 2018

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Alzheimer's disease and the amyloid-beta peptide

23 May 2018

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Methodologies to assess brain drug delivery in lead optimization

23 May 2018

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Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

23 May 2018

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Cytochrome P450 reaction-phenotyping: an industrial perspective

23 May 2018

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Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction

23 May 2018

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Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

23 May 2018

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Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure-activity relationship (QSAR) with the Abraham descriptors.

23 May 2018

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Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833

23 May 2018

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Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling

23 May 2018

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Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone.

23 May 2018

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Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer's Disease

23 May 2018

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Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS.

15 August 2018

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Altered brain uptake of therapeutics in a triple transgenic mouse model of Alzheimer's disease

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703966

Inhibition of beta-amyloid peptide aggregation by multifunctional carbazole-based fluorophores.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703966

Development of a high-throughput brain slice method for studying drug distribution in the central nervous system

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703966

Effect of P-glycoprotein inhibitor, verapamil, on oral bioavailability and pharmacokinetics of irinotecan in rats

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703966

ADMET--turning chemicals into drugs

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41598-017-16635-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41598-017-16635-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Physiological parameters in laboratory animals and humans

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41598-017-16635-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41598-017-16635-4

1 reference

8 January 2018

Dimensions Publication ID

0 references

1 reference

8 January 2018

PubMed publication ID

29180684

1 reference

8 January 2018