(Q47107803)

8 January 2018

title

Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines (English)

1 reference

8 January 2018

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33

Meenhard Herlyn

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8 January 2018

12

Keith T Flaherty

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8 January 2018

3

Clemens Krepler

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PMC publication ID

5709812

8 January 2018

Katherine L Nathanson

34

Katherine L Nathanson

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8 January 2018

26

Melissa A Wilson

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8 January 2018

Tara C Gangadhar

14

Tara C Gangadhar

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8 January 2018

Jennifer Wargo

24

Jennifer Wargo

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8 January 2018

Giorgos Karakousis

17

Giorgos Karakousis

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8 January 2018

Nicholas J Petrelli

20

Nicholas J Petrelli

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8 January 2018

4

Patricia Brafford

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8 January 2018

22

Batool Shannan

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8 January 2018

5

Katrin Sproesser

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8 January 2018

21

Lynn Schuchter

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8 January 2018

10

Marilda Beqiri

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8 January 2018

25

Brandon Wenz

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8 January 2018

Bradley Garman

1

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8 January 2018

Ioannis N Anastopoulos

2

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8 January 2018

Yuchao Jiang

6

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8 January 2018

Bradley Wubbenhorst

7

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8 January 2018

Ravi Amaravadi

8

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8 January 2018

Joseph Bennett

9

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8 January 2018

David Elder

11

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8 January 2018

Dennie T Frederick

13

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8 January 2018

Michael Guarino

15

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8 January 2018

David Hoon

16

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8 January 2018

Qin Liu

18

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8 January 2018

Nandita Mitra

19

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8 January 2018

Carol L Shields

23

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8 January 2018

Min Xiao

27

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8 January 2018

Wei Xu

28

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8 January 2018

Xaiowei Xu

29

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8 January 2018

Xiangfan Yin

30

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8 January 2018

Nancy R Zhang

31

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8 January 2018

Michael A Davies

32

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8 January 2018

publication date

1 November 2017

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8 January 2018

published in

Cell Reports

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8 January 2018

volume

21

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8 January 2018

issue

7

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8 January 2018

page(s)

1936-1952

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8 January 2018

describes a project that uses

RStudio

1 reference

18 June 2022

https://europepmc.org/article/PMC/5709812

based on heuristic

inferred from PubMed Central ID database lookup

cites work

NF1-mutated melanoma tumors harbor distinct clinical and biological characteristics

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A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers

23 May 2018

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Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients

23 May 2018

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Analysis of protein-coding genetic variation in 60,706 humans

23 May 2018

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Building a Robust Tumor Profiling Program: Synergy between Next-Generation Sequencing and Targeted Single-Gene Testing

23 May 2018

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RAS isoforms and mutations in cancer at a glance

23 May 2018

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Annual Report to the Nation on the Status of Cancer, 1975-2012, featuring the increasing incidence of liver cancer

23 May 2018

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The genomic landscape of cutaneous melanoma

23 May 2018

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Personalized Preclinical Trials in BRAF Inhibitor-Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies

23 May 2018

1 reference

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Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms

23 May 2018

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SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2

23 May 2018

1 reference

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Recurrent inactivating RASA2 mutations in melanoma

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Genomic Classification of Cutaneous Melanoma

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

CODEX: a normalization and copy number variation detection method for whole exome sequencing

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Improved overall survival in melanoma with combined dabrafenib and trametinib

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

23 May 2018

UV signature mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

23 May 2018

Management of melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

ARID1B is a specific vulnerability in ARID1A-mutant cancers.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Mixed Lineage Kinase-c-Jun N-Terminal Kinase Axis: A Potential Therapeutic Target in Cancer

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

An integrated map of genetic variation from 1,092 human genomes

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

A landscape of driver mutations in melanoma

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Melanoma genome sequencing reveals frequent PREX2 mutations

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

23 May 2018

1 reference

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Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

23 May 2018

1 reference

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Patient-derived tumour xenografts as models for oncology drug development

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

A framework for variation discovery and genotyping using next-generation DNA sequencing data

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

23 May 2018

1 reference

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ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Fast and accurate short read alignment with Burrows-Wheeler transform

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Spectrum of MEK1 and MEK2 gene mutations in cardio-facio-cutaneous syndrome and genotype-phenotype correlations

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

Mutations of the BRAF gene in human cancer

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5709812

10.1016/J.CELREP.2017.10.052

15 August 2018

Identifiers

DOI

1 reference

8 January 2018

PMC publication ID

5709812

1 reference

8 January 2018

PubMed publication ID

29141224

1 reference

8 January 2018