(Q47117559)

English

Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability

scientific article published on 13 December 2017

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scholarly article

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Europe PubMed Central

PMC publication ID

8 January 2018

http://europepmc.org/abstract/PMC/5727486

Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability (English)

1 reference

Europe PubMed Central

PMC publication ID

8 January 2018

http://europepmc.org/abstract/PMC/5727486

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Clostridium difficile

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Geoffrey Mcmullan

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29235503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

6

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13 June 2020

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29235503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Shailesh Jain

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29235503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Deborah Smyth

2

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13 June 2020

Barry M G O'Hagan

3

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13 June 2020

John T Heap

4

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13 June 2020

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13 December 2017

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Europe PubMed Central

PMC publication ID

8 January 2018

http://europepmc.org/abstract/PMC/5727486

Scientific Reports

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13 June 2020

7

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Europe PubMed Central

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13 June 2020

1

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Europe PubMed Central

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13 June 2020

17522

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29235503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

copyright license

Creative Commons Attribution 4.0 International

1 December 2017

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April 2022 Public Data File from Crossref

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https://scigraph.springernature.com/pub.10.1038/s41598-017-17583-9

0 references

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Adaptive strategies and pathogenesis of Clostridium difficile from in vivo transcriptomics

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1 reference

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Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations

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Clostridium difficile transcriptome analysis using pig ligated loop model reveals modulation of pathways not modulated in vitro

1 reference

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The key sigma factor of transition phase, SigH, controls sporulation, metabolism, and virulence factor expression in Clostridium difficile

1 reference

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Fourteen-genome comparison identifies DNA markers for severe-disease-associated strains of Clostridium difficile

1 reference

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Important role of class I heat shock genes hrcA and dnaK in the heat shock response and the response to pH and NaCl stress of group I Clostridium botulinum strain ATCC 3502

1 reference

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The emergence of 'hypervirulence' in Clostridium difficile

1 reference

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Evolutionary dynamics of Clostridium difficile over short and long time scales

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Pseudomonas aeruginosa cystic fibrosis isolates of similar RAPD genotype exhibit diversity in biofilm forming ability in vitro.

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Characterization of the sporulation initiation pathway of Clostridium difficile and its role in toxin production

1 reference

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23 May 2018

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

1 reference

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Motility and flagellar glycosylation in Clostridium difficile.

1 reference

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Clostridium difficile infection: new developments in epidemiology and pathogenesis

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Type IV pili and the CcpA protein are needed for maximal biofilm formation by the gram-positive anaerobic pathogen Clostridium perfringens

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Historical perspectives on studies of Clostridium difficile and C. difficile infection

1 reference

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SigB-dependent general stress response in Bacillus subtilis and related gram-positive bacteria

1 reference

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Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains

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GroES/GroEL and DnaK/DnaJ have distinct roles in stress responses and during cell cycle progression in Caulobacter crescentus.

1 reference

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The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

1 reference

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GroEL of Lactobacillus johnsonii La1 (NCC 533) is cell surface associated: potential role in interactions with the host and the gastric pathogen Helicobacter pylori

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FtsZ and the division of prokaryotic cells and organelles

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Clostridium difficile-associated diarrhea in adults

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The DnaK/DnaJ chaperone machinery of Salmonella enterica serovar Typhimurium is essential for invasion of epithelial cells and survival within macrophages, leading to systemic infection

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Global transcriptional response of Bacillus subtilis to heat shock

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Role of FliC and FliD flagellar proteins of Clostridium difficile in adherence and gut colonization

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Induced levels of heat shock proteins in a dnaK mutant of Lactococcus lactis

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The dnaK operon of Bacillus subtilis is heptacistronic

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DnaK mutants defective in ATPase activity are defective in negative regulation of the heat shock response: expression of mutant DnaK proteins results in filamentation

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Escherichia coli dnaK null mutants are inviable at high temperature

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DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32.

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Quantitative proteomic analysis of the heat stress response in Clostridium difficile strain 630.

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15 August 2018

Proteomic analysis of the insoluble subproteome of Clostridium difficile strain 630.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5727486

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7 January 2021

based on heuristic

inferred from DOI database lookup

Post-transcriptional regulation of the Bacillus subtilis dnaK operon

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-17583-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Negative regulation of bacterial heat shock genes

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-17583-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Generation of an erythromycin-sensitive derivative of Clostridium difficile strain 630 (630Deltaerm) and demonstration that the conjugative transposon Tn916DeltaE enters the genome of this strain at multiple sites

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-17583-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/S41598-017-17583-9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29235503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29235503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29235503%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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