(Q47155991)

9 January 2018

title

Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis (English)

1 reference

9 January 2018

author

Dominik Aschenbrenner

Dominik Aschenbrenner

7

0 references

Maria Bokarewa

Maria Bokarewa

15

0 references

Samuele Notarbartolo

Samuele Notarbartolo

2

0 references

Karin M Andersson

Karin M Andersson

8

0 references

Nathalie Pochet

Nathalie Pochet

17

0 references

Federica Sallusto

18

Federica Sallusto

1 reference

9 January 2018

20

Howard L Weiner

1 reference

9 January 2018

author name string

Dan Hu

1

1 reference

9 January 2018

Tom Croonenborghs

3

1 reference

9 January 2018

Bonny Patel

4

1 reference

9 January 2018

Ron Cialic

5

1 reference

9 January 2018

Tun-Hsiang Yang

6

1 reference

9 January 2018

Marco Gattorno

9

1 reference

9 January 2018

Minh Pham

10

1 reference

9 January 2018

Pia Kivisakk

11

1 reference

9 January 2018

Isabelle V Pierre

12

1 reference

9 January 2018

Youjin Lee

13

1 reference

9 January 2018

Karun Kiani

14

1 reference

9 January 2018

Emily Tjon

16

1 reference

9 January 2018

Vijay K Kuchroo

19

1 reference

9 January 2018

language of work or name

English

0 references

publication date

17 November 2017

1 reference

9 January 2018

published in

Nature Communications

1 reference

9 January 2018

volume

8

1 reference

9 January 2018

issue

1

1 reference

9 January 2018

page(s)

1600

1 reference

9 January 2018

Creative Commons Attribution 4.0 International

copyright license

start time

17 November 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/s41467-017-01571-8

0 references

cites work

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Tbet or Continued RORγt Expression Is Not Required for Th17-Associated Immunopathology.

23 May 2018

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Th1/Th17 plasticity is a marker of advanced β cell autoimmunity and impaired glucose tolerance in humans

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Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids.

23 May 2018

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Th17/IL-17A might play a protective role in chronic lymphocytic leukemia immunity

23 May 2018

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T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease

23 May 2018

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Highly polarized Th17 cells induce EAE via a T-bet independent mechanism

23 May 2018

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Immune system: a double-edged sword in cancer

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Cutting edge: the pathogenicity of IFN-γ-producing Th17 cells is independent of T-bet

23 May 2018

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Induction and molecular signature of pathogenic TH17 cells

23 May 2018

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23 May 2018

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Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

23 May 2018

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TH17 deficiency in human disease

23 May 2018

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T helper 17 cell heterogeneity and pathogenicity in autoimmune disease

23 May 2018

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Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity

23 May 2018

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Regulation and functions of the IL-10 family of cytokines in inflammation and disease

23 May 2018

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Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

T helper 17 cells promote cytotoxic T cell activation in tumor immunity

23 May 2018

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A protective function for interleukin 17A in T cell-mediated intestinal inflammation

23 May 2018

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23 May 2018

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IL-23 and Th17 cytokines in intestinal homeostasis

23 May 2018

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Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

23 May 2018

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Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

23 May 2018

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Tumor-specific Th17-polarized cells eradicate large established melanoma

23 May 2018

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Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers.

23 May 2018

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TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

23 May 2018

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23 May 2018

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Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

23 May 2018

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A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

23 May 2018

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Nonredundant roles for Stat5a/b in directly regulating Foxp3

23 May 2018

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

23 May 2018

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Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Adjusting batch effects in microarray expression data using empirical Bayes methods

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Expression of chemokines in the CSF and correlation with clinical disease activity in patients with multiple sclerosis.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Th17 cells: A prognostic marker for MS rebound after natalizumab cessation?

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Inflammatory cytokines at the summits of pathological signal cascades in brain diseases

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Secukinumab failure in Crohn's disease: the yeast connection?

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

The Ifng gene is essential for Vdr gene expression and vitamin D₃-mediated reduction of the pathogenic T cell burden in the central nervous system in experimental autoimmune encephalomyelitis, a multiple sclerosis model.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

T-bet is essential for the progression of experimental autoimmune encephalomyelitis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Interferon-gamma confers resistance to experimental allergic encephalomyelitis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5693957

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

15 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41467-017-01571-8

7 January 2021

Multiple sclerosis: a study of CXCL10 and CXCR3 co-localization in the inflamed central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FS41467-017-01571-8

7 January 2021

CCL5, CXCL10 and CXCL11 chemokines in patients with active and stable relapsing-remitting multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41467-017-01571-8

7 January 2021

Induction of the chemokine receptor CXCR3 on TCR-stimulated T cells: dependence on the release from persistent TCR-triggering and requirement for IFN-gamma stimulation

1 reference

https://api.crossref.org/works/10.1038%2FS41467-017-01571-8

7 January 2021

10.1038/S41467-017-01571-8

Identifiers

DOI

1 reference

9 January 2018

0 references

1 reference

9 January 2018

PubMed publication ID

29150604

1 reference

9 January 2018