(Q47160621)

10 January 2018

title

Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis (English)

1 reference

10 January 2018

Débora Barbosa Vendramini-Costa

1 reference

object named as

Débora Barbosa Vendramini-Costa

1

0 references

author name string

Ralph Francescone

2

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10 January 2018

David Posocco

3

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10 January 2018

Vivianty Hou

4

1 reference

10 January 2018

Oxana Dmitrieva

5

1 reference

10 January 2018

Harvey Hensley

6

1 reference

10 January 2018

João Ernesto de Carvalho

7

1 reference

10 January 2018

Ronaldo Aloise Pilli

8

1 reference

10 January 2018

Sergei I Grivennikov

9

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10 January 2018

language of work or name

English

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publication date

24 October 2016

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10 January 2018

published in

Carcinogenesis

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10 January 2018

volume

38

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10 January 2018

issue

1

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10 January 2018

page(s)

51-63

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10 January 2018

Aspirin and Colorectal Cancer Prevention and Treatment: Is It for Everyone?

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Goniothalamin prevents the development of chemically induced and spontaneous colitis in rodents and induces apoptosis in the HT-29 human colon tumor cell line

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Chitinase 3-like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitis-associated cancer by regulating S100A9.

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Spontaneous Intestinal Tumorigenesis in Apc (/Min+) Mice Requires Altered T Cell Development with IL-17A.

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Gastroprotective effects of goniothalamin against ethanol and indomethacin-induced gastric lesions in rats: Role of prostaglandins, nitric oxide and sulfhydryl compounds

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A new goniothalamin N-acylated aza-derivative strongly downregulates mediators of signaling transduction associated with pancreatic cancer aggressiveness

23 May 2018

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Design and synthesis of N-acylated aza-goniothalamin derivatives and evaluation of their in vitro and in vivo antitumor activity

23 May 2018

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23 May 2018

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Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity

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Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis.

23 May 2018

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Cytokines in inflammatory bowel disease

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Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation

23 May 2018

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Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model

23 May 2018

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Natural products: a continuing source of novel drug leads

23 May 2018

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Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases

23 May 2018

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IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation

23 May 2018

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Inflammation and colorectal cancer: colitis-associated neoplasia

23 May 2018

1 reference

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IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

23 May 2018

1 reference

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Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

23 May 2018

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Chemoprotection against cancer by isothiocyanates: a focus on the animal models and the protective mechanisms

23 May 2018

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Molecular link mechanisms between inflammation and cancer

23 May 2018

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Non-steroidal anti-inflammatory drugs and colorectal cancer risk in a large, prospective cohort

23 May 2018

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S100A8/A9 activate key genes and pathways in colon tumor progression

23 May 2018

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Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials

23 May 2018

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Effect of goniothalamin on the development of Ehrlich solid tumor in mice

23 May 2018

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Immunity, Inflammation, and Cancer

23 May 2018

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Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis

23 May 2018

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23 May 2018

Eicosanoids and cancer

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NF-kappaB as a critical link between inflammation and cancer

23 May 2018

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Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens.

23 May 2018

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The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

Systematic review of the association between circulating interleukin-6 (IL-6) and cancer

23 May 2018

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Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis

23 May 2018

1 reference

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NF-kappaB: linking inflammation and immunity to cancer development and progression

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

(R)-Goniothalamin: total syntheses and cytotoxic activity against cancer cell lines

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.

23 May 2018

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Anti-inflammatory therapies in TRAMP mice: delay in PCa progression.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

Neutrophil infiltration favors colitis-associated tumorigenesis by activating the interleukin-1 (IL-1)/IL-6 axis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

Opposing consequences of IL-23 signaling mediated by innate and adaptive cells in chemically induced colitis in mice.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

The increased expression of IL-23 in inflammatory bowel disease promotes intraepithelial and lamina propria lymphocyte inflammatory responses and cytotoxicity

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

Gnotobiotic IL-10-/-;NF-kappa B(EGFP) mice reveal the critical role of TLR/NF-kappa B signaling in commensal bacteria-induced colitis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

Synthesis and biological evaluation of cytostatin analogues

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5219049

Increased Susceptibility to Colitis-Associated Cancer of Mice Lacking TIR8, an Inhibitory Member of the Interleukin-1 Receptor Family

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGW112

Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27797827

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A simplified method of evaluating dose-effect experiments

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27797827

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/CARCIN/BGW112

1 reference

10 January 2018

PMCID

5219049

1 reference

10 January 2018

PubMed ID

27797827

1 reference

10 January 2018