(Q47180993)

7 July 2018

title

Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma (English)

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7 July 2018

author

Jonathan Goldin

18

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7 July 2018

Keith M. Sullivan

1

Keith M Sullivan

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7 July 2018

9

Leslie J Crofford

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7 July 2018

Ellen A. Goldmuntz

2

Ellen A Goldmuntz

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7 July 2018

E. William St. Clair

19

E William St Clair

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7 July 2018

Chitra Hosing

28

Chitra Hosing

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7 July 2018

author name string

Lynette Keyes-Elstein

3

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7 July 2018

Peter A McSweeney

4

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7 July 2018

Ashley Pinckney

5

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7 July 2018

Beverly Welch

6

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7 July 2018

Maureen D Mayes

7

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7 July 2018

Richard A Nash

8

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7 July 2018

Barry Eggleston

10

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7 July 2018

Sharon Castina

11

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7 July 2018

Linda M Griffith

12

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7 July 2018

Julia S Goldstein

13

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7 July 2018

Dennis Wallace

14

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7 July 2018

Oana Craciunescu

15

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7 July 2018

Dinesh Khanna

16

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7 July 2018

Rodney J Folz

17

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7 July 2018

James R Seibold

20

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7 July 2018

Kristine Phillips

21

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7 July 2018

Shin Mineishi

22

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7 July 2018

Robert W Simms

23

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7 July 2018

Karen Ballen

24

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7 July 2018

Mark H Wener

25

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7 July 2018

George E Georges

26

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7 July 2018

Shelly Heimfeld

27

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7 July 2018

Stephen Forman

29

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7 July 2018

Suzanne Kafaja

30

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7 July 2018

Richard M Silver

31

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7 July 2018

Leroy Griffing

32

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7 July 2018

Jan Storek

33

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7 July 2018

Sharon LeClercq

34

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7 July 2018

Richard Brasington

35

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7 July 2018

Mary E Csuka

36

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7 July 2018

Christopher Bredeson

37

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7 July 2018

Carolyn Keever-Taylor

38

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7 July 2018

Robyn T Domsic

39

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7 July 2018

M Bashar Kahaleh

40

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7 July 2018

Thomas Medsger

41

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7 July 2018

Daniel E Furst

42

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7 July 2018

SCOT Study Investigators

43

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7 July 2018

language of work or name

English

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publication date

1 January 2018

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7 July 2018

The New England Journal of Medicine

published in

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7 July 2018

volume

378

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7 July 2018

issue

1

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7 July 2018

page(s)

35-47

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7 July 2018

Manufacture of Autologous CD34+ Selected Grafts in the NIAID-Sponsored HALT-MS and SCOT Multicenter Clinical Trials for Autoimmune Diseases

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial

10 July 2018

1 reference

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Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Review: Hematopoietic Stem Cell Transplantation for Scleroderma: Effective Immunomodulatory Therapy for Patients With Pulmonary Involvement

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Secondary malignancies following high dose therapy and autologous hematopoietic cell transplantation-systematic review and meta-analysis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

T cell repertoire following autologous stem cell transplantation for multiple sclerosis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Dexpramipexole versus placebo for patients with amyotrophic lateral sclerosis (EMPOWER): a randomised, double-blind, phase 3 trial

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Cancer incidence in systemic sclerosis: meta-analysis of population-based cohort studies

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Gastric antral vascular ectasia and its clinical correlates in patients with early diffuse systemic sclerosis in the SCOT trial.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

The Combined Assessment of Function and Survival (CAFS): a new endpoint for ALS clinical trials

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Complications of autologous hematopoietic stem cell transplantation for patients with autoimmune diseases.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Trends in mortality in patients with systemic sclerosis over 40 years: a systematic review and meta-analysis of cohort studies

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Autologous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Renal shielding and dosimetry for patients with severe systemic sclerosis receiving immunoablation with total body irradiation in the scleroderma: cyclophosphamide or transplantation trial

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Acute kidney injury in patients with systemic sclerosis participating in hematopoietic cell transplantation trials in the United States

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Methodological issues in the use of composite endpoints in clinical trials: examples from the HIV field

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Hematopoietic cell transplantation for autoimmune disease: updates from Europe and the United States

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years' experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Effects of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Minimally important difference in diffuse systemic sclerosis: results from the D-penicillamine study

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Recovery from and consequences of severe iatrogenic lymphopenia (induced to treat autoimmune diseases).

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Minimizing predictability while retaining balance through the use of less restrictive randomization procedures

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Development and Evolution of a Hierarchical Clinical Composite End Point for the Evaluation of Drugs and Devices for Acute and Chronic Heart Failure: A 20-Year Perspective.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Rebooting autoimmunity with autologous HSCT.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Cardiac involvement and treatment-related mortality after non-myeloablative haemopoietic stem-cell transplantation with unselected autologous peripheral blood for patients with systemic sclerosis: a retrospective analysis.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Skin thickness score in systemic sclerosis: an assessment of interobserver variability in 3 independent studies.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846574

Treatment of systemic sclerosis with autologous haemopoietic stem cell transplantation

14 August 2018

1 reference

12 December 2020

Combining mortality and longitudinal measures in clinical trials

1 reference

12 December 2020

Conditioning regimens for the treatment of experimental arthritis with autologous bone marrow transplantation

1 reference

12 December 2020

Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network

1 reference

12 December 2020

Prediction of pulmonary complications and long-term survival in systemic sclerosis

1 reference

12 December 2020

Identifiers

DOI

10.1056/NEJMOA1703327

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7 July 2018

PMCID

5846574

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7 July 2018

PubMed ID

29298160

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7 July 2018