(Q47182414)

11 January 2018

title

Single-chromosome Gains Commonly Function as Tumor Suppressors (English)

1 reference

11 January 2018

author

Zuzana Storchova

9

1 reference

11 January 2018

Angelika Amon

10

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11 January 2018

author name string

Jason M Sheltzer

1

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11 January 2018

Julie H Ko

2

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11 January 2018

John M Replogle

3

1 reference

11 January 2018

Nicole C Habibe Burgos

4

1 reference

11 January 2018

Erica S Chung

5

1 reference

11 January 2018

Colleen M Meehl

6

1 reference

11 January 2018

Nicole M Sayles

7

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11 January 2018

Verena Passerini

8

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11 January 2018

publication date

29 December 2016

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11 January 2018

published in

Cancer Cell

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11 January 2018

volume

31

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11 January 2018

page(s)

240-255

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11 January 2018

issue

2

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11 January 2018

Kinetic Analysis of Protein Stability Reveals Age-Dependent Degradation

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23 May 2018

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23 May 2018

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Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast

23 May 2018

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HSF1 deficiency and impaired HSP90-dependent protein folding are hallmarks of aneuploid human cells.

23 May 2018

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Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

23 May 2018

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Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast.

23 May 2018

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Unique features of the transcriptional response to model aneuploidy in human cells

23 May 2018

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Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome

23 May 2018

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Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors.

23 May 2018

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Pan-cancer patterns of somatic copy number alteration

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation

23 May 2018

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Aneuploidy causes proteotoxic stress in yeast

23 May 2018

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Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells.

23 May 2018

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Acute leukemias in children with Down syndrome

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Transcriptional consequences of aneuploidy

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Causes and consequences of aneuploidy in cancer.

23 May 2018

1 reference

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DNA breaks and chromosome pulverization from errors in mitosis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

The aneuploidy paradox: costs and benefits of an incorrect karyotype

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Aneuploidy drives genomic instability in yeast

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Identification of aneuploidy-selective antiproliferation compounds

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Identification of aneuploidy-tolerating mutations

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Loss of spindle assembly checkpoint-mediated inhibition of Cdc20 promotes tumorigenesis in mice

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Effects of aneuploidy on cellular physiology and cell division in haploid yeast

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Mad2 overexpression promotes aneuploidy and tumorigenesis in mice

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Does aneuploidy cause cancer?

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Adenovirus E1A: remodelling the host cell, a life or death experience

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

How aneuploidy may cause cancer and genetic instability

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Trisomy 21 is a recurrent secondary aberration in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

How aneuploidy affects metabolic control and causes cancer

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Increasing complexity of the karyotype in 50 human gliomas. Progressive evolution and de novo occurrence of cytogenetic alterations

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

Aneuploidy acts both oncogenically and as a tumor suppressor

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5713901

MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation

14 August 2018

1 reference

12 December 2020

Increasing genomic instability during premalignant neoplastic progression revealed through high resolution array-CGH

1 reference

12 December 2020

DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance

1 reference

12 December 2020

In vivo aneuploidization during the expansion of renal adenocarcinoma

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12 December 2020

Tumorigenesis in Down's syndrome: big lessons from a small chromosome

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12 December 2020

Karyotypic evolution in human malignant melanoma

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12 December 2020

10.1016/J.CCELL.2016.12.004

Identifiers

DOI

1 reference

11 January 2018

PMCID

5713901

1 reference

11 January 2018

PubMed ID

28089890

1 reference

11 January 2018