(Q47248700)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29278283%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

review article

1 reference

title

Delirium pathophysiology: An updated hypothesis of the etiology of acute brain failure (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29278283%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29278283%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

author name string

José R Maldonado

series ordinal

1

1 reference

http://europepmc.org/abstract/MED/29278283

12 January 2018

language of work or name

English

0 references

publication date

26 December 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29278283%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Geriatric Psychiatry

8 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29278283%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29278283%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29278283%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

page(s)

1428-1457

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29278283%20AND%20SRC:MED&resulttype=core&format=json

Delirium in the acute care setting: characteristics, diagnosis and treatment

8 April 2020

cites work

1 reference

Acute Brain Failure: Pathophysiology, Diagnosis, Management, and Sequelae of Delirium

21 January 2018

1 reference

The prognostic significance of subsyndromal delirium in elderly medical inpatients

21 January 2018

1 reference

Evaluation of delirium in elderly: a hospital-based study.

21 January 2018

1 reference

Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration

21 January 2018

1 reference

21 January 2018

1 reference

Neuron numbers and dendritic extent in normal aging and Alzheimer's disease

21 January 2018

1 reference

Loss of cerebral white matter structural integrity tracks the gray matter metabolic decline in normal aging

21 January 2018

1 reference

The neurobiology of aging

21 January 2018

1 reference

Neuroanatomical changes associated with cognitive aging

21 January 2018

1 reference

Cortisol levels and neuropsychiatric diagnosis as markers of postoperative delirium: a prospective cohort study

21 January 2018

1 reference

Postoperative delirium: age and low functional reserve as independent risk factors

21 January 2018

1 reference

Observational, longitudinal study of delirium in consecutive unselected acute medical admissions: age-specific rates and associated factors, mortality and re-admission

21 January 2018

1 reference

Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients

21 January 2018

1 reference

Executive function and depression as independent risk factors for postoperative delirium

21 January 2018

1 reference

Post-operative delirium is associated with poor cognitive outcome and dementia.

21 January 2018

1 reference

Delirium risk factors in elderly hospitalized patients

21 January 2018

1 reference

Risk factors for delirium at discharge: development and validation of a predictive model.

21 January 2018

1 reference

The risk of dementia and death after delirium.

21 January 2018

1 reference

Neuropathogenesis of delirium: review of current etiologic theories and common pathways

21 January 2018

1 reference

Pathoetiological model of delirium: a comprehensive understanding of the neurobiology of delirium and an evidence-based approach to prevention and treatment

21 January 2018

1 reference

Systemic infection and delirium: when cytokines and acetylcholine collide

21 January 2018

1 reference

The role of inflammation in the pathogenesis of delirium and dementia in older adults: a review.

21 January 2018

1 reference

Systemic inflammation and delirium: important co-factors in the progression of dementia.

21 January 2018

1 reference

Cytokines and acute phase response in delirium

21 January 2018

1 reference

Cytokines and C-reactive protein production in hip-fracture-operated elderly patients.

21 January 2018

1 reference

The neuroinflammatory hypothesis of delirium

21 January 2018

1 reference

Age and neuroinflammation: a lifetime of psychoneuroimmune consequences.

21 January 2018

1 reference

Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease

21 January 2018

1 reference

Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.

21 January 2018

1 reference

Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium.

21 January 2018

1 reference

From inflammation to sickness and depression: when the immune system subjugates the brain

21 January 2018

1 reference

Activation of vascular endothelial cells and perivascular cells by systemic inflammation-an immunohistochemical study of postmortem human brain tissues

21 January 2018

1 reference

Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations

21 January 2018

1 reference

Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood-brain barrier permeability: Possible link to postoperative delirium and cognitive decline.

21 January 2018

1 reference

The blood-brain barrier in systemic inflammation

21 January 2018

1 reference

An update on the role of free radicals and antioxidant defense in human disease

21 January 2018

1 reference

Free radicals and antioxidants in normal physiological functions and human disease

21 January 2018

1 reference

The role of oxidative stress in postoperative delirium.

21 January 2018

1 reference

Cognitive decline is associated with systemic oxidative stress: the EVA study. Etude du Vieillissement Artériel.

21 January 2018

1 reference

Mechanisms of brain injury after global cerebral ischemia

21 January 2018

1 reference

Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain

21 January 2018

1 reference

Direct evidence for acute and massive norepinephrine release in the hippocampus during transient ischemia

21 January 2018

1 reference

Prediction of postoperative delirium after abdominal surgery in the elderly

21 January 2018

1 reference

Preoperative regional cerebral oxygen saturation is a predictor of postoperative delirium in on-pump cardiac surgery patients: a prospective observational trial

21 January 2018

1 reference

Cerebral circulation and metabolism

21 January 2018

1 reference

Relationships between glutamate release, blood flow and spreading depression: real-time monitoring using an electroenzymatic dialysis electrode

21 January 2018

1 reference

Glutamate neurotoxicity, calcium, and zinc

21 January 2018

1 reference

Calcium-dependent glutamate release concomitant with massive potassium flux during cerebral ischemia in vivo

21 January 2018

1 reference

Impaired synthesis of acetylcholine in brain accompanying mild hypoxia and hypoglycemia

21 January 2018

1 reference

Post-ischemic regional changes in acetylcholine synthesis following transient forebrain ischemia in gerbils

21 January 2018

1 reference

Selective alteration of neurotransmitter release by low oxygen in vitro

21 January 2018

1 reference

Glucocorticoids and central nervous system inflammation

21 January 2018

1 reference

Stress, Glucocorticoids, and Damage to the Nervous System: The Current State of Confusion.

21 January 2018

1 reference

Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders

21 January 2018

1 reference

The stressed CNS: when glucocorticoids aggravate inflammation.

21 January 2018

1 reference

Smaller left anterior cingulate cortex volumes are associated with impaired hypothalamic-pituitary-adrenal axis regulation in healthy elderly men.

21 January 2018

1 reference

Glucocorticoid actions on synapses, circuits, and behavior: implications for the energetics of stress

21 January 2018

1 reference

Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness

21 January 2018

1 reference

Glucocorticoid hypersecretion and the age-impaired hippocampus: cause or effect?

21 January 2018

1 reference

Why stress is bad for your brain

21 January 2018

1 reference

Unravelling the pathophysiology of delirium: a focus on the role of aberrant stress responses

21 January 2018

1 reference

Aging in the hippocampus: interrelated actions of neurotrophins and glucocorticoids

21 January 2018

1 reference

Effects of glucocorticoids on hippocampal long-term potentiation.

21 January 2018

1 reference

Cognitive dysfunction, hippocampal atrophy and glucocorticoid feedback in Alzheimer's disease

21 January 2018

1 reference

Hyperactivity in the hypothalamic-pituitary-adrenal axis in demented patients with delirium

21 January 2018

1 reference

Activity in the hypothalamic-pituitary-adrenal axis and delirium.

21 January 2018

1 reference

Cerebrospinal fluid cortisol levels are higher in patients with delirium versus controls

21 January 2018

1 reference

The effects of stress and stress hormones on human cognition: Implications for the field of brain and cognition

21 January 2018

1 reference

The "steroid dementia syndrome": a possible model of human glucocorticoid neurotoxicity

21 January 2018

1 reference

Chronic stress, cognitive functioning and mental health

21 January 2018

1 reference

Beta-endorphin, cortisol and postoperative delirium: a preliminary report.

21 January 2018

1 reference

Pattern of activation of the hypothalamic-pituitary-adrenal axis in acute stroke. Relation to acute confusional state, extent of brain damage, and clinical outcome.

21 January 2018

1 reference

Glucocorticoids potentiate ischemic injury to neurons: therapeutic implications.

21 January 2018

1 reference

Mechanisms of stress in the brain

21 January 2018

1 reference

Delirium, steroids, and cardiac surgery

21 January 2018

1 reference

Corticosteroid-induced delirium and dependency

21 January 2018

1 reference

New-onset psychiatric disorders after corticosteroid therapy in systemic lupus erythematosus: an observational case-series study.

21 January 2018

1 reference

Corticosteroids and transition to delirium in patients with acute lung injury

21 January 2018

1 reference

Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects.

21 January 2018

1 reference

Corticosteroid-induced psychiatric disturbances: It is time for pharmacists to take notice.

21 January 2018

1 reference

Cortisol is an associated-risk factor of brain dysfunction in patients with severe sepsis and septic shock

21 January 2018

1 reference

Combination of inhaled corticosteroid and bronchodilator-induced delirium in an elderly patient with lung disease.

21 January 2018

1 reference

Severe neuropsychiatric outcomes following discontinuation of long-term glucocorticoid therapy: a cohort study.

21 January 2018

1 reference

The basic physiology and pathophysiology of melatonin

21 January 2018

1 reference

Physiological effects of melatonin: role of melatonin receptors and signal transduction pathways

21 January 2018

1 reference

Basic aspects of melatonin action.

21 January 2018

1 reference

Phototransduction by retinal ganglion cells that set the circadian clock

21 January 2018

1 reference

Kynurenine pathway inhibition as a therapeutic strategy for neuroprotection

21 January 2018

1 reference

Sleep in acute care units

21 January 2018

1 reference

Sleep deprivation as a neurobiologic and physiologic stressor: Allostasis and allostatic load

21 January 2018

1 reference

Sedative and analgesic medications: risk factors for delirium and sleep disturbances in the critically ill.

21 January 2018

1 reference

Circadian disruption: New clinical perspective of disease pathology and basis for chronotherapeutic intervention

21 January 2018

1 reference

Impaired circadian rhythm of melatonin secretion in sedated critically ill patients with severe sepsis

21 January 2018

1 reference

Correlation between serum melatonin circadian rhythm and intensive care unit psychosis after thoracic esophagectomy

21 January 2018

1 reference

Abolished circadian rhythm of melatonin secretion in sedated and artificially ventilated intensive care patients

21 January 2018

1 reference

The relation between the clinical subtypes of delirium and the urinary level of 6-SMT.

21 January 2018

1 reference

Melatonin therapy to improve nocturnal sleep in critically ill patients: encouraging results from a small randomised controlled trial

21 January 2018

1 reference

Assessment of role of perioperative melatonin in prevention and treatment of postoperative delirium after hip arthroplasty under spinal anesthesia in the elderly.

21 January 2018

1 reference

The effects of melatonin versus placebo on delirium in hip fracture patients: study protocol of a randomised, placebo-controlled, double blind trial

21 January 2018

1 reference

Exogenous Melatonin for Delirium Prevention: a Meta-analysis of Randomized Controlled Trials

21 January 2018

1 reference

Pathophysiology of delirium.

21 January 2018

1 reference

Psychotogenic drugs and delirium pathogenesis: the central role of the thalamus.

21 January 2018

1 reference

The neuropathogenesis of delirium. A need to focus our research

21 January 2018

1 reference

Characterization and propagation of uncertainty in diffusion-weighted MR imaging

21 January 2018

1 reference

Imaging functional and structural brain connectomics in attention-deficit/hyperactivity disorder

21 January 2018

1 reference

Fiber tracking: principles and strategies - a technical review

21 January 2018

1 reference

Enhanced brain small-worldness after sleep deprivation: a compensatory effect.

21 January 2018

1 reference

Collective dynamics of 'small-world' networks

21 January 2018

1 reference

The human brain is intrinsically organized into dynamic, anticorrelated functional networks

21 January 2018

1 reference

Neural network functional connectivity during and after an episode of delirium

21 January 2018

1 reference

Decreased functional connectivity between the mediodorsal thalamus and default mode network in patients with disorders of consciousness.

21 January 2018

1 reference

The putative impact of metabolic health on default mode network activity and functional connectivity in neuropsychiatric disorders

21 January 2018

1 reference

Default mode network connectivity is linked to cognitive functioning and CSF Aβ1-42 levels in Alzheimer's disease.

21 January 2018

1 reference

An investigation into the functional and structural connectivity of the Default Mode Network

21 January 2018

1 reference

Functional connectivity in the resting brain: a network analysis of the default mode hypothesis

21 January 2018

1 reference

Changes in default mode network as automaticity develops in a categorization task

21 January 2018

1 reference

The structural–functional connectome and the default mode network of the human brain

21 January 2018

1 reference

Default mode network activity and connectivity in psychopathology

21 January 2018

1 reference

Hypothesis for the pathophysiology of delirium: role of baseline brain network connectivity and changes in inhibitory tone.

21 January 2018

1 reference

Delirium: a subcortical phenomenon?

21 January 2018

1 reference

Loss of effective connectivity during general anesthesia

21 January 2018

1 reference

Orexins: looking forward to sleep, back at addiction

21 January 2018

1 reference

Control of sleep and wakefulness

21 January 2018

1 reference

Resting-state Network-specific Breakdown of Functional Connectivity during Ketamine Alteration of Consciousness in Volunteers

21 January 2018

1 reference

The involvement of hypothalamic sleep pathways in general anesthesia: testing the hypothesis using the GABAA receptor beta3N265M knock-in mouse

21 January 2018

1 reference

The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness

21 January 2018

1 reference

Orexin neuronal circuitry: role in the regulation of sleep and wakefulness

21 January 2018

1 reference

Hypothalamic regulation of sleep and circadian rhythms

21 January 2018

1 reference

Sleep and delirium in ICU patients: a review of mechanisms and manifestations

21 January 2018

1 reference

Interleukin-1beta enhances GABAA receptor cell-surface expression by a phosphatidylinositol 3-kinase/Akt pathway: relevance to sepsis-associated encephalopathy.

21 January 2018

1 reference

Lipopolysaccharide challenge-induced suppression of Fos in hypothalamic orexin neurons: their potential role in sickness behavior

21 January 2018

1 reference

Disruption of large-scale brain systems in advanced aging

21 January 2018

1 reference

White matter abnormalities as a risk factor for postoperative delirium revealed by diffusion tensor imaging

21 January 2018

1 reference

White-Matter Hyperintensities Predict Delirium After Cardiac Surgery

21 January 2018

1 reference

Neural mechanisms of ageing and cognitive decline

21 January 2018

1 reference

Evolution of the aging brain transcriptome and synaptic regulation

21 January 2018

1 reference

21 January 2018

1 reference

21 January 2018

1 reference

Cortical cholinergic inputs mediating arousal, attentional processing and dreaming: differential afferent regulation of the basal forebrain by telencephalic and brainstem afferents

21 January 2018

1 reference

Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence

21 January 2018

1 reference

21 January 2018

Subsyndromal Delirium

1 reference

7 January 2021

Subtle Attentional Deficits in the Absence of Dementia Are Associated with an Increased Risk of Post-Operative Delirium

1 reference

7 January 2021

Pathophysiology of postoperative delirium: systemic inflammation as a response to surgical trauma causes diffuse microcirculatory impairment

1 reference

7 January 2021

Incidence, risk factors and consequences of ICU delirium

1 reference

7 January 2021

Delirium, a syndrome of cerebral insufficiency

1 reference

7 January 2021

Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis

1 reference

7 January 2021

Temporal relationship between neurotransmitter release and ion flux during spreading depression and anoxia

1 reference

7 January 2021

Aging Decreases Oxidative Metabolism and the Release and Synthesis of Acetylcholine

1 reference

7 January 2021

Dopamine and serotonin in rat striatum during in vivo hypoxic-hypoxia

1 reference

7 January 2021

Delirium and the dexamethasone suppression test in the elderly

1 reference

7 January 2021

Glucocorticoids, hippocampal damage and the glutamatergic synapse

1 reference

7 January 2021

Physiological elevations of glucocorticoids potentiate glutamate accumulation in the hippocampus.

1 reference

7 January 2021

Dexamethasone effects on cortisol secretion in Alzheimer’s disease: Some clinical and hormonal features in suppressor and nonsuppressor patients

1 reference

7 January 2021

Abnormal cortisol response in Alzheimer's disease linked to hippocampal atrophy

1 reference

7 January 2021

Sleep and delirium after open heart surgery

1 reference

7 January 2021

CNS Arousal Systems: Possible Role in Delirium

1 reference

7 January 2021

Identifiers

DOI

10.1002/GPS.4823

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29278283%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference