(Q35022584)

5 August 2017

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title

Glucocorticoids and central nervous system inflammation (English)

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5 August 2017

3

Robert M Sapolsky

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5 August 2017

Klaus Dinkel

1

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PubMed ID

12476346

5 August 2017

William O Ogle

series ordinal

2

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5 August 2017

1 December 2002

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5 August 2017

Journal of NeuroVirology

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5 August 2017

8

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5 August 2017

6

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5 August 2017

513-528

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https://scigraph.springernature.com/pub.10.1080/13550280290100914

5 August 2017

0 references

cites work

Glucocorticoid and mineralocorticoid resistance/hypersensitivity syndromes

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12 December 2020

Corticosteroids suppress cyclooxygenase messenger RNA levels and prostanoid synthesis in cultured vascular cells

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12 December 2020

A review of the adrenal cortex and severe inflammation: quest of the "eucorticoid" state

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12 December 2020

Dexamethasone-induced abolition of the inflammatory response in an experimental glioma model: a flow cytometry study.

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12 December 2020

Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation

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12 December 2020

Glucocorticoid administration accelerates mortality of pneumovirus-infected mice.

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12 December 2020

Memory--a century of consolidation

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12 December 2020

The hepatic interleukin-6 receptor. Studies on its structure and regulation by phorbol 12-myristate 13-acetate-dexamethasone

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12 December 2020

Mechanisms of excitotoxicity in neurologic diseases

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12 December 2020

Immunopathologic weight loss in intracranial LCMV infection initiated by the anorexigenic effects of IL-1beta

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12 December 2020

Adrenal steroid receptors and actions in the nervous system

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12 December 2020

Clinical management of brain metastasis

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12 December 2020

HIV type 1 Nef protein is a viral factor for leukocyte recruitment into the central nervous system

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12 December 2020

Brain corticosteroid receptor balance in health and disease

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12 December 2020

Glucocorticoids and immune function: unknown dimensions and new frontiers

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12 December 2020

Transient induction of cytokine production in human myocardial fibroblasts by coxsackievirus B3.

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12 December 2020

Cytokines and hormones as possible links between endocrinosenescence and immunosenescence

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12 December 2020

Why do neuroprotective drugs work in animals but not humans?

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12 December 2020

A comparison of the effects of human and ovine corticotropin-releasing hormone on the pituitary-adrenal axis

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12 December 2020

Poliovirus protein 3A inhibits tumor necrosis factor (TNF)-induced apoptosis by eliminating the TNF receptor from the cell surface

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12 December 2020

Corticosteroids or ACTH for acute exacerbations in multiple sclerosis

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12 December 2020

Development of the blood-brain barrier

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12 December 2020

Macrophage migration inhibitory factor: a regulator of glucocorticoid activity with a critical role in inflammatory disease.

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12 December 2020

How the glucocorticoids suppress immunity

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12 December 2020

Increased neutrophil mobilization and decreased chemotaxis during cortisol and epinephrine infusions

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12 December 2020

Glucocorticoids potentiate ischemic injury to neurons: therapeutic implications.

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12 December 2020

ENTEROVIRUS-INDUCED PRODUCTION OF PRO-INFLAMMATORY AND T-HELPER CYTOKINES BY HUMAN LEUKOCYTES

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12 December 2020

Early response of brain resident microglia to kainic acid-induced hippocampal lesions.

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12 December 2020

The role of inflammation after acute stroke: utility of pursuing anti-adhesion molecule therapy.

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12 December 2020

Cytokine-gene expression in measles-infected adult human glial cells

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12 December 2020

Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

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12 December 2020

Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation?

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12 December 2020

Dexamethasone therapy worsens the neuropathology of human immunodeficiency virus type 1 encephalitis in SCID mice

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12 December 2020

Neurotransmitter-induced hypothalamic-pituitary-adrenal axis responsiveness is defective in inflammatory disease-susceptible Lewis rats: in vivo and in vitro studies suggesting globally defective hypothalamic secretion of corticotropin-releasing hor

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12 December 2020

The neuroimmunology of stress from invertebrates to man.

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12 December 2020

Application of dexamethasone in the treatment of acute spinal cord injury

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12 December 2020

Basic aspects of neuroimmunology as they relate to immunotherapeutic targets: present and future prospects

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12 December 2020

Up-regulation of the interleukin-6-signal transducing protein (gp130) by interleukin-6 and dexamethasone in HepG2 cells

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12 December 2020

Why stress is bad for your brain

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12 December 2020

Glucocorticoids exacerbate kainic acid-induced extracellular accumulation of excitatory amino acids in the rat hippocampus

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12 December 2020

Macrophages and the Nervous System

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12 December 2020

Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?

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12 December 2020

Stress-induced enhancement of antigen-specific cell-mediated immunity.

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12 December 2020

MIF as a glucocorticoid-induced modulator of cytokine production

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12 December 2020

Enhanced Replication of Human Cytomegalovirus in Human Fibroblasts Treated with Dexamethasone

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12 December 2020

Endogenous glucocorticoids protect against cytokine-mediated lethality during viral infection

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12 December 2020

Anti-inflammatory actions of steroids: molecular mechanisms

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12 December 2020

Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord I

1 reference

12 December 2020

Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection

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12 December 2020

Glucocorticoids inhibit apoptosis of human neutrophils

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12 December 2020

Differential regulation of lipopolysaccharide-induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary-adrenal axis

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12 December 2020

Steroids for multiple sclerosis and optic neuritis: a meta-analysis of randomized controlled clinical trials

1 reference

12 December 2020

Viral infection induces cytokine release by beta islet cells

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12 December 2020

Pathobiology of ischaemic stroke: an integrated view

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12 December 2020

Stress, corticotropin-releasing hormone, glucocorticoids, and the immune/inflammatory response: acute and chronic effects

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12 December 2020

Clinical and immunological considerations in Epstein-Barr virus-associated diseases.

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12 December 2020

Transactivation of the interleukin-1alpha promoter by human T-cell leukemia virus type I and type II Tax proteins

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12 December 2020

Induction of immunoreactive interleukin-1 beta and tumor necrosis factor-alpha in the brains of rabies virus infected rats

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12 December 2020

Tumor necrosis factor alpha expression in the spinal cord of human T-cell lymphotrophic virus type I associated myelopathy/tropical spastic paraparesis patients

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12 December 2020

A novel permissive role for glucocorticoids in induction of febrile and behavioral signs of experimental herpes simplex virus encephalitis.

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12 December 2020

Induction of cytokine receptors by glucocorticoids: functional and pathological significance

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12 December 2020

IL-2 protects T cell hybrids from the cytolytic effect of glucocorticoids. Synergistic effect of IL-2 and dexamethasone in the induction of high-affinity IL-2 receptors

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12 December 2020

The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease

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12 December 2020

Differential effects of nerve growth factor and dexamethasone on herpes simplex virus type 1 oriL- and oriS-dependent DNA replication in PC12 cells.

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12 December 2020

Mutagenesis of the glucocorticoid receptor in mice

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12 December 2020

Corticosteroid modulation of hippocampal potentials: increased effect with aging

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12 December 2020

Glucocorticoids in central nervous system bacterial infection

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12 December 2020

Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats

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12 December 2020

Targeting the central nervous system inflammatory response in ischemic stroke.

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12 December 2020

Role of epinephrine in TNF and IL-6 production from isolated perfused rat liver

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12 December 2020

Protective autoimmunity is a physiological response to CNS trauma.

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12 December 2020

Role of the hypothalamic pituitary adrenal axis and IL-6 in stress-induced reactivation of latent herpes simplex virus type 1.

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12 December 2020

Chronic stress in caregivers of dementia patients is associated with reduced lymphocyte sensitivity to glucocorticoids.

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12 December 2020

Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors

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12 December 2020

Differential induction of cytokines by primary and persistent measles virus infections in human glial cells

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12 December 2020

A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock

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12 December 2020

Infection of peripheral blood mononuclear cells by herpes simplex and Epstein-Barr viruses. Differential induction of interleukin 6 and tumor necrosis factor-alpha

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12 December 2020

Complement and cytokine gene expression in cultured microglial derived from postmortem human brains

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12 December 2020

Cytotoxicity of microglia

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12 December 2020

Glucocorticoid mechanisms in acute spinal cord injury: a review and therapeutic rationale

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12 December 2020

A randomized controlled trial of prednisone in Alzheimer's disease. Alzheimer's Disease Cooperative Study.

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12 December 2020

Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1.

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12 December 2020

Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage.

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12 December 2020

[Levels of interleukin-6 in cerebrospinal fluid of patients with meningitis]

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12 December 2020

A vision of cell death: insights into immune privilege

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12 December 2020

Stress-associated immune modulation: relevance to viral infections and chronic fatigue syndrome

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12 December 2020

Migration inhibitory factor induces killing of Leishmania major by macrophages: dependence on reactive nitrogen intermediates and endogenous TNF-alpha

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12 December 2020

The acute-phase response protects mice from D-galactosamine sensitization to endotoxin and tumor necrosis factor–α

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12 December 2020

MIF rediscovered: cytokine, pituitary hormone, and glucocorticoid-induced regulator of the immune response

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12 December 2020

The role of the hippocampus in feedback regulation of the hypothalamic-pituitary-adrenocortical axis

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12 December 2020

Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways

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12 December 2020

In the presence of dexamethasone, gamma interferon induces rat oligodendrocytes to express major histocompatibility complex class II molecules

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12 December 2020

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

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12 December 2020

Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation.

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12 December 2020

Bright and dark sides of nitric oxide in ischemic brain injury

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12 December 2020

Chronic dexamethasone pretreatment aggravates ischemic neuronal necrosis.

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12 December 2020

Glucocorticoids stimulate inflammatory 5-lipoxygenase gene expression and protein translocation in the brain.

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12 December 2020

Cerebral ischemia and inflammation

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12 December 2020

Is Ca2+ -activated potassium efflux involved in the formation of ischemic brain edema?

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12 December 2020

A nuclear factor for interleukin-6 expression (NF-IL6) and the glucocorticoid receptor synergistically activate transcription of the rat alpha 1-acid glycoprotein gene via direct protein-protein interaction

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12 December 2020

Corticosteroids and traumatic brain injury: status at the end of the decade of the brain.

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12 December 2020

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

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12 December 2020

Herpes simplex replication and dissemination is not increased by corticosteroid treatment in a rat model of focal Herpes encephalitis

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12 December 2020

Corticosteroids for treating Guillain-Barré syndrome

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12 December 2020

Molecular mechanisms of anti-inflammatory action of glucocorticoids

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12 December 2020

Brain Aging Correlates: Retardation by Hormonal-Pharmacological Treatments

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12 December 2020

Excitatory amino acids as a final common pathway for neurologic disorders.

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12 December 2020

Dexamethasone-induced suppression of apoptosis in human neutrophils requires continuous stimulation of new protein synthesis

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12 December 2020

Exercise and circadian rhythm-induced variations in plasma cortisol differentially regulate interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor-alpha (TNF alpha) production in humans: high sensitivity of TNF alpha and resistance of IL-6

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12 December 2020

Chronic corticosterone treatment maintains synaptic activity of CA1 hippocampal pyramidal cells: acute high corticosterone administration increases action potential number

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12 December 2020

Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthma

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12 December 2020

Effect of dexamethasone on elevated cytokine mRNA levels in chemical-induced hippocampal injury.

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12 December 2020

Regulation of L-selectin and CD18 on bovine neutrophils by glucocorticoids: effects of cortisol and dexamethasone

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12 December 2020

A mechanism for glucocorticoid toxicity in the hippocampus: increased neuronal vulnerability to metabolic insults.

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12 December 2020

How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions

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12 December 2020

Dexamethasone inhibition of interleukin 1 beta production by human monocytes. Posttranscriptional mechanisms

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12 December 2020

Plasma membrane calcium pump isoform 1 gene expression is repressed by corticosterone and stress in rat hippocampus

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12 December 2020

Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature.

1 reference

12 December 2020

HIV-1 envelope glycoprotein 120 regulates brain IL-1beta system and TNF-alpha mRNAs in vivo

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12 December 2020

Patterns of cytokine gene expression in infectious mononucleosis.

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12 December 2020

Brain inflammation in Alzheimer disease and the therapeutic implications

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12 December 2020

The neurobiology of stress: from serendipity to clinical relevance

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12 December 2020

Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage

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12 December 2020

Macrophage migration inhibitory factor in rheumatoid arthritis: evidence of proinflammatory function and regulation by glucocorticoids

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12 December 2020

Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: a potential role for leukocyte trafficking.

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12 December 2020

Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones

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12 December 2020

Synergism for cytokine-mediated disease during concurrent endotoxin and viral challenges: roles for NK and T cell IFN-gamma production

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12 December 2020

Glucocorticoid receptor-binding site in the human immunodeficiency virus long terminal repeat

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12 December 2020

Identification of a glucocorticoid-responsive element in Epstein-Barr virus.

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12 December 2020

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

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12 December 2020

The changing landscape of ischaemic brain injury mechanisms.

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12 December 2020

Corticosteroid actions in the hippocampus

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12 December 2020

Cytokines, glucocorticoids and lipocortins in the control of neutrophil migration

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12 December 2020

Stress effects on morphology and function of the hippocampus

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12 December 2020

Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice.

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12 December 2020

Measles virus infection enhances IL-1 beta but reduces tumor necrosis factor-alpha expression in human monocytes

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12 December 2020

Neuronal apoptosis mediated by IL-1 beta expression in viral encephalitis caused by a neuroadapted strain of the mumps virus (Kilham Strain) in hamsters

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12 December 2020

Effects of glucocorticoids and norepinephrine on the excitability in the hippocampus

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12 December 2020

Aging, energy, and oxidative stress in neurodegenerative diseases.

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12 December 2020

The hypothalamic-pituitary-adrenal-immune axis. A critical assessment

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12 December 2020

Release of TNF alpha in the rat hippocampus following epileptic seizures and excitotoxic neuronal damage

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12 December 2020

Novel glucocorticoid effects on acute inflammation in the CNS.

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12 December 2020

The sexual differentiation of social play

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12 December 2020

Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing?

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12 December 2020

Glucocorticoids and stress: permissive and suppressive actions

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12 December 2020

CD95-CD95L: can the brain learn from the immune system?

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12 December 2020

Protective and damaging effects of stress mediators

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12 December 2020

NF-kappa B: a crucial transcription factor for glial and neuronal cell function

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12 December 2020

Dexamethasone inhibits the induction of monocyte chemotactic-activating factor production by IL-1 or tumor necrosis factor.

1 reference

12 December 2020

A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

1 reference

12 December 2020

Neuroendocrine-immune interactions during viral infections

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12 December 2020

Modulation of interleukin-1 and tumor necrosis factor expression by ?-adrenergic agonists in mouse ameboid microglial cells

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12 December 2020

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats.

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12 December 2020

Use of dexamethasone in treatment of cerebral edema associated with brain tumors.

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12 December 2020

Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1.

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12 December 2020

The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone; compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis

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12 December 2020

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12 December 2020

Current concepts of excitotoxicity.

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12 December 2020

Abnormalities of brain perfusion in echovirus type 30 meningitis

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12 December 2020

AIDS dementia is associated with massive, activated HIV-1 infection and concomitant expression of several cytokines.

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12 December 2020

Steroid controversy in sepsis and septic shock: a meta-analysis

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12 December 2020

Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals

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12 December 2020

Inflammatory mediators and stroke: new opportunities for novel therapeutics

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12 December 2020

Aging-associated up-regulation of neuronal 5-lipoxygenase expression: putative role in neuronal vulnerability

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12 December 2020

Species differences in the generation of reactive oxygen species by microglia

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12 December 2020

Proinflammatory cytokines and early neurological worsening in ischemic stroke

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12 December 2020

Beneficial immune activity after CNS injury: prospects for vaccination

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12 December 2020

Inflammation and acute stroke

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12 December 2020

Microglia: a sensor for pathological events in the CNS

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12 December 2020

The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation

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12 December 2020

Learning deficits in mice with persistent Borna disease virus infection of the CNS associated with elevated chemokine expression

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12 December 2020

Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man

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12 December 2020

Long-term corticosteroid treatment of myasthenia gravis: report of 116 patients

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12 December 2020

Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.

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12 December 2020

Persistent inflammatory response in stroke survivors

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12 December 2020

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

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12 December 2020

Absence of the p55 Kd TNF-alpha receptor promotes survival in rabies virus acute encephalitis

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12 December 2020

Cytokines and their receptors in the central nervous system: physiology, pharmacology, and pathology

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12 December 2020

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12 December 2020

Control of glial immune function by neurons

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12 December 2020

Inflammation and stroke: benefits without harm?

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12 December 2020

Junctions in the central nervous system of the cat. IV. Interendothelial junctions of cerebral blood vessels from selected areas of the brain

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12 December 2020

Inflammation after stroke: is it harmful?

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12 December 2020

Chronic stress in elderly carers of dementia patients and antibody response to influenza vaccination.

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12 December 2020

Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress.

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12 December 2020

Poliovirus 3A protein limits interleukin-6 (IL-6), IL-8, and beta interferon secretion during viral infection

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12 December 2020

Circulating interleukin-6 levels are elevated in adult T-cell leukaemia/lymphoma patients and correlate with adverse clinical features and survival

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12 December 2020

Steroids in the treatment of brain edema.

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12 December 2020

Inflammation and glial responses in ischemic brain lesions.

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12 December 2020

Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor

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12 December 2020

New Glucocorticosteroids with an improved therapeutic ratio?

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12 December 2020

Glucocorticoid therapy for immune-mediated diseases: basic and clinical correlates

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12 December 2020

Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia

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12 December 2020

Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging

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12 December 2020

Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction

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12 December 2020

Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress

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12 December 2020

Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor.

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12 December 2020

The physiological relevance of glucocorticoid endangerment of the hippocampus

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12 December 2020

Human herpesvirus 6 induces IL-8 gene expression in human hepatoma cell line, Hep G2

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12 December 2020

Interleukin-1 receptor antagonist attenuates regional neuronal cell death and cognitive dysfunction after experimental brain injury.

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12 December 2020

Stress and the brain: a paradoxical role for adrenal steroids

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12 December 2020

Induction of hypoxia inducible factor 1 by oxygen glucose deprivation is attenuated by hypoxic preconditioning in rat cultured neurons.

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12 December 2020

A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1

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12 December 2020

The acute phase response

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12 December 2020

Glucocorticosteroid-dependent synergy between interleukin 1 and interleukin 6 for human B lymphocyte differentiation

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12 December 2020

Stress-induced changes in blood leukocyte distribution. Role of adrenal steroid hormones

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12 December 2020

Dexamethasone blocks antioestrogen- and oxidant-induced death of pituitary tumour cells

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12 December 2020

Steroids and spinal cord injury: revisiting the NASCIS 2 and NASCIS 3 trials

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12 December 2020

10.1080/13550280290100914

Identifiers

DOI

1 reference

PubMed ID

12476346

Dimensions Publication ID

5 August 2017

0 references

1 reference

PubMed ID

12476346