(Q47271945)

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title

Hyperbaric oxygen treatment suppresses MAPK signaling and mitochondrial apoptotic pathway in degenerated human intervertebral disc cells (English)

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main subject

intervertebral disc cell

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6

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author name string

Chi-Chien Niu

1

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Song-Shu Lin

2

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Li-Jen Yuan

3

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Lih-Huei Chen

4

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I-Chun Wang

5

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Po-Liang Lai

7

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Wen-Jer Chen

8

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publication date

6 August 2012

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Journal of Orthopaedic Research

published in

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volume

31

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issue

2

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page(s)

204-209

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Occurrence and regional distribution of apoptosis in scoliotic discs.

cites work

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An autocrine or paracrine Fas-mediated counterattack: a potential mechanism for apoptosis of notochordal cells in intact rat nucleus pulposus.

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MAPK signalling pathways as molecular targets for anti-inflammatory therapy--from molecular mechanisms to therapeutic benefits

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c-Jun N-terminal kinase and, to a lesser extent, p38 mitogen-activated protein kinase regulate inducible nitric oxide synthase expression in hyaluronan fragments-stimulated BV-2 microglia

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Beneficial effects of hyperbaric oxygen on human degenerated intervertebral disk cells via suppression of IL-1β and p38 MAPK signal.

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ZL11n is a novel nitric oxide-releasing derivative of farnesylthiosalicylic acid that induces apoptosis in human hepatoma HepG2 cells via MAPK/mitochondrial pathways

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ERK1/2 and p38 mitogen-activated protein kinase mediate iNOS-induced spinal neuron degeneration after acute traumatic spinal cord injury

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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Apoptosis of human intervertebral discs after trauma compares to degenerated discs involving both receptor-mediated and mitochondrial-dependent pathways.

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Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax.

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Regulation of apoptosis by Bcl‐2 family proteins

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Hyperbaric oxygen preconditioning reduces ischemia-reperfusion injury by inhibition of apoptosis via mitochondrial pathway in rat brain.

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Hyperbaric oxygen attenuates apoptosis and decreases inflammation in an ischemic wound model

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Therapeutic effects of hyperbaric oxygen in a rat model of endothelin-1-induced focal cerebral ischemia

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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Effects of different exposures of hyperbaric oxygen on ligament healing in rats

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Hypoxia activates MAPK activity in rat nucleus pulposus cells: regulation of integrin expression and cell survival

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Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

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Bax directly induces release of cytochrome c from isolated mitochondria

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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Neuroprotective effect of hyperbaric oxygen therapy in brain injury is mediated by preservation of mitochondrial membrane properties

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Mitochondria as targets of apoptosis regulation by nitric oxide

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Identifiers

DOI

10.1002/JOR.22209

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