(Q47274054)

3 March 2018

title

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study (English)

1 reference

3 March 2018

genome-wide association study

main subject

0 references

dementia

1 reference

based on heuristic

inferred from title

dementia with Lewy bodies

1 reference

65

1 reference

3 March 2018

Kevin Morgan

Kevin Morgan

29

0 references

Stuart Pickering-Brown

Stuart Pickering-Brown

57

0 references

Mónica Díez-Fairen

Monica Diez-Fairen

43

0 references

Claire E Shepherd

Claire E Shepherd

7

0 references

Henrik Zetterberg

25

Henrik Zetterberg

1 reference

3 March 2018

38

Suzanne Lesage

1 reference

PMCID

5805394

3 March 2018

Valentina Escott-Price

53

Valentina Escott-Price

1 reference

3 March 2018

22

Ekaterina Rogaeva

1 reference

3 March 2018

49

Andrew Lees

1 reference

3 March 2018

40

Eliezer Masliah

1 reference

3 March 2018

60

John Hardy

1 reference

3 March 2018

24

Elisabet Londos

1 reference

3 March 2018

1

Rita Guerreiro

1 reference

3 March 2018

51

Ronald C Petersen

1 reference

3 March 2018

2

Owen A Ross

1 reference

3 March 2018

63

Andrew Singleton

1 reference

3 March 2018

30

Claire Troakes

1 reference

3 March 2018

37

Thomas G Beach

1 reference

3 March 2018

56

John C Morris

1 reference

3 March 2018

Nigel J Cairns

55

Nigel J Cairns

1 reference

3 March 2018

Tammaryn Lashley

32

Tammaryn Lashley

1 reference

3 March 2018

John Q. Trojanowski

61

John Q Trojanowski

1 reference

3 March 2018

Dena G. Hernandez

4

Dena G Hernandez

1 reference

3 March 2018

Lee Darwent

9

0 references

Janice Holton

33

Janice Holton

1 reference

3 March 2018

Karen S. Marder

20

Karen Marder

1 reference

3 March 2018

Lorraine Clark

18

Lorraine Clark

1 reference

3 March 2018

Kristelle Brown

28

Kristelle Brown

1 reference

3 March 2018

47

Minna Oinas

1 reference

3 March 2018

5

Tatiana Orme

1 reference

3 March 2018

8

Laura Parkkinen

1 reference

3 March 2018

36

Geidy E Serrano

1 reference

3 March 2018

31

Safa Al-Sarraj

1 reference

3 March 2018

46

Liisa Myllykangas

1 reference

3 March 2018

27

Anne Braae

1 reference

3 March 2018

Celia Kun-Rodrigues

3

1 reference

3 March 2018

John D Eicher

6

1 reference

3 March 2018

Michael G Heckman

10

1 reference

3 March 2018

Juan C Troncoso

12

1 reference

3 March 2018

Olga Pletnikova

13

1 reference

3 March 2018

Olaf Ansorge

14

1 reference

3 March 2018

Jordi Clarimon

15

1 reference

3 March 2018

Alberto Lleo

16

1 reference

3 March 2018

Estrella Morenas-Rodriguez

17

1 reference

3 March 2018

Lawrence S Honig

19

1 reference

3 March 2018

Afina Lemstra

21

1 reference

3 March 2018

Peter St George-Hyslop

23

1 reference

3 March 2018

Imelda Barber

26

1 reference

3 March 2018

Yaroslau Compta

34

1 reference

3 March 2018

Vivianna Van Deerlin

35

1 reference

3 March 2018

Douglas Galasko

39

1 reference

3 March 2018

Isabel Santana

41

1 reference

3 March 2018

Miquel Aguilar

44

1 reference

3 March 2018

Pentti J Tienari

45

1 reference

3 March 2018

Tamas Revesz

48

1 reference

3 March 2018

Brad F Boeve

50

1 reference

3 March 2018

Tanis J Ferman

52

1 reference

3 March 2018

Neill Graff-Radford

54

1 reference

3 March 2018

David Mann

58

1 reference

3 March 2018

Glenda M Halliday

59

1 reference

3 March 2018

Dennis W Dickson

62

1 reference

3 March 2018

David J Stone

64

1 reference

3 March 2018

publication date

16 December 2017

1 reference

3 March 2018

published in

Lancet Neurology

1 reference

3 March 2018

volume

17

1 reference

3 March 2018

issue

1

1 reference

3 March 2018

page(s)

64-74

1 reference

3 March 2018

describes a project that uses

genome-wide association study

1 reference

based on heuristic

inferred from title

cites work

The role of Gpi-anchored axonal glycoproteins in neural development and neurological disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Reference-based phasing using the Haplotype Reference Consortium panel

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Next-generation genotype imputation service and methods

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

A reference panel of 64,976 haplotypes for genotype imputation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Analysis of protein-coding genetic variation in 60,706 humans

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Exome sequencing in dementia with Lewy bodies

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Haploinsufficiency of the STX1B gene is associated with myoclonic astatic epilepsy

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Genome-wide association study of neocortical Lewy-related pathology

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Second-generation PLINK: rising to the challenge of larger and richer datasets

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Systematic identification of trans eQTLs as putative drivers of known disease associations

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

APOE ε4 increases risk for dementia in pure synucleinopathies

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Imputation across genotyping arrays for genome-wide association studies: assessment of bias and a correction strategy

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

TREM2 Variants in Alzheimer's Disease

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

A two-stage meta-analysis identifies several new loci for Parkinson's disease

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Rare-variant association testing for sequencing data with the sequence kernel association test

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Estimating missing heritability for disease from genome-wide association studies

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Common SNPs explain a large proportion of the heritability for human height

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

GWAMA: software for genome-wide association meta-analysis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Mutations in contactin-1, a neural adhesion and neuromuscular junction protein, cause a familial form of lethal congenital myopathy

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

A novel locus for dementia with Lewy bodies: a clinically and genetically heterogeneous disorder

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

A systematic review of prevalence and incidence studies of dementia with Lewy bodies

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Dementia with Lewy bodies according to the consensus criteria in a general population aged 75 years or older

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Characterization of a presynaptic glutamate receptor

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Isolation and characterization of a membrane glycoprotein from human brain with sequence similarities to cell adhesion proteins from chicken and mouse

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5805394

10.1016/S1474-4422(17)30400-3

14 August 2018

Identifiers

DOI

1 reference

3 March 2018

PMCID

5805394

1 reference

3 March 2018

PubMed ID

29263008

1 reference

3 March 2018