(Q47315201)

English

Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial

scientific article published on 19 July 2017

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Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

mechanical ventilation

1 reference

based on heuristic

inferred from title

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based on heuristic

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based on heuristic

inferred from title

Eugene Wesley Ely

3

object named as

E Wesley Ely

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

author name string

Valerie J Page

1

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

Annalisa Casarin

2

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

Xiao Bei Zhao

4

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

Cliona McDowell

5

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

Lynn Murphy

6

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

Daniel F McAuley

7

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

publication date

19 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

The Lancet. Respiratory medicine

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Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

5

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

9

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

727-737

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

Prevalence, risk factors, and outcomes of delirium in mechanically ventilated adults.

1 reference

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Long-term cognitive impairment after critical illness

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Costs associated with delirium in mechanically ventilated patients

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The cholinergic system and inflammation: common pathways in delirium pathophysiology

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Inflammation biomarkers and delirium in critically ill patients

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Cerebrospinal fluid markers of neuroinflammation in delirium: a role for interleukin-1β in delirium after hip fracture

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Neuroinflammation in delirium: a postmortem case-control study

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Simvastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo.

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Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury

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7 January 2021

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Statins and delirium during critical illness: a multicenter, prospective cohort study

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7 January 2021

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Statin use and risk of delirium in the critically ill.

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7 January 2021

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Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood-brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron cell death

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Rosuvastatin versus placebo for delirium in intensive care and subsequent cognitive impairment in patients with sepsis-associated acute respiratory distress syndrome: an ancillary study to a randomised controlled trial

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7 January 2021

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Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial.

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Association between statin therapy and outcomes in critically ill patients: a nested cohort study.

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Simvastatin in the acute respiratory distress syndrome

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Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for intensive care patients: observational multicentre study

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The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients

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Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU).

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Telephone assessment of cognitive function in adulthood: the Brief Test of Adult Cognition by Telephone.

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The Informant Questionnaire on cognitive decline in the elderly (IQCODE): a review

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https://api.crossref.org/works/10.1016%2FS2213-2600%2817%2930234-5

7 January 2021

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Early Intensive Care Sedation Predicts Long-Term Mortality in Ventilated Critically Ill Patients

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2817%2930234-5

7 January 2021

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Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2817%2930234-5

7 January 2021

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Statistical methods for evaluating delirium in the ICU.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2817%2930234-5

7 January 2021

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The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure

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https://api.crossref.org/works/10.1016%2FS2213-2600%2817%2930234-5

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The association between computer use and cognition across adulthood: Use it so you won't lose it?

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Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis

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Routine use of the confusion assessment method for the intensive care unit: a multicenter study.

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Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit.

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Haloperidol prophylaxis in critically ill patients with a high risk for delirium

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Sedation depth and long-term mortality in mechanically ventilated critically ill adults: a prospective longitudinal multicentre cohort study

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Rapidly reversible, sedation-related delirium versus persistent delirium in the intensive care unit

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Identifiers

10.1016/S2213-2600(17)30234-5

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 January 2018

http://europepmc.org/abstract/MED/28734823

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