(Q47334271)

14 January 2018

title

DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development (English)

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14 January 2018

hypogonadotropic hypogonadism

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22

Nelly Pitteloud

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14 January 2018

author name string

Justine Bouilly

1

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14 January 2018

Andrea Messina

2

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14 January 2018

Georgios Papadakis

3

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14 January 2018

Daniele Cassatella

4

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14 January 2018

Cheng Xu

5

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14 January 2018

James S Acierno

6

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14 January 2018

Brooke Tata

7

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14 January 2018

Gerasimos Sykiotis

8

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14 January 2018

Sara Santini

9

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14 January 2018

Yisrael Sidis

10

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14 January 2018

Eglantine Elowe-Gruau

11

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14 January 2018

Franziska Phan-Hug

12

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14 January 2018

Michael Hauschild

13

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14 January 2018

Pierre-Marc Bouloux

14

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14 January 2018

Richard Quinton

15

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14 January 2018

Mariarosaria Lang-Muritano

16

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14 January 2018

Lucie Favre

17

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14 January 2018

Laura Marino

18

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14 January 2018

Paolo Giacobini

19

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14 January 2018

Andrew A Dwyer

20

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14 January 2018

Nicolas J Niederländer

21

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14 January 2018

publication date

30 November 2017

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14 January 2018

published in

Human Molecular Genetics

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14 January 2018

volume

27

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14 January 2018

issue

2

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14 January 2018

page(s)

359-372

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14 January 2018

From nose to brain: development of gonadotrophin-releasing hormone-1 neurones

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Netrin 1-mediated chemoattraction regulates the migratory pathway of LHRH neurons

21 January 2018

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Netrin/DCC signaling guides olfactory sensory axons to their correct location in the olfactory bulb

21 January 2018

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Congenital mirror movements: mutational analysis of RAD51 and DCC in 26 cases

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The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1.

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An ancient founder mutation in PROKR2 impairs human reproduction

21 January 2018

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Germline prokineticin receptor 2 (PROKR2) variants associated with central hypogonadism cause differental modulation of distinct intracellular pathways

21 January 2018

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SEMA3A, a gene involved in axonal pathfinding, is mutated in patients with Kallmann syndrome

21 January 2018

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Functionally compromised CHD7 alleles in patients with isolated GnRH deficiency.

21 January 2018

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GNRH1 mutations in patients with idiopathic hypogonadotropic hypogonadism

21 January 2018

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Cell migration from the olfactory placode and the ontogeny of the neuroendocrine compartments

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Composition of the migratory mass during development of the olfactory nerve

21 January 2018

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Neural crest and ectodermal cells intermix in the nasal placode to give rise to GnRH-1 neurons, sensory neurons, and olfactory ensheathing cells

21 January 2018

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Development of the neurons controlling fertility in humans: new insights from 3D imaging and transparent fetal brains.

21 January 2018

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The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

21 January 2018

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Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

21 January 2018

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21 January 2018

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N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors

21 January 2018

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Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin

21 January 2018

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Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism

21 January 2018

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Signaling mechanism of the netrin-1 receptor DCC in axon guidance

21 January 2018

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Filopodia: molecular architecture and cellular functions

21 January 2018

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21 January 2018

Life at the leading edge

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Differential regulation of myosin X movements by its cargos, DCC and neogenin.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDX408

KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX408

Defective signaling through plexin-A1 compromises the development of the peripheral olfactory system and neuroendocrine reproductive axis in mice.

21 January 2018

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21 January 2018

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21 January 2018

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Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDX408

Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX408

21 January 2018

Identifiers

DOI

10.1093/HMG/DDX408

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14 January 2018

PubMed ID

29202173

1 reference

14 January 2018