(Q47337001)

14 January 2018

title

Man versus machine: is there an optimal method for QT measurements in thorough QT studies? (English)

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14 January 2018

author name string

Borje Darpo

1

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14 January 2018

Marilyn Agin

2

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14 January 2018

David J Kazierad

3

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14 January 2018

Gary Layton

4

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14 January 2018

Gary Muirhead

5

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14 January 2018

Peter Gray

6

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14 January 2018

Diane K Jorkasky

7

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14 January 2018

publication date

1 June 2006

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14 January 2018

The Journal of Clinical Pharmacology

published in

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14 January 2018

volume

46

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14 January 2018

page(s)

598-612

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14 January 2018

issue

6

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14 January 2018

Drug-induced torsades de pointes and implications for drug development.

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Drug induced QT prolongation and torsades de pointes

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Variability of the QTc interval: impact on defining drug effect and low-frequency cardiac event

21 January 2018

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Electrocardiographic and clinical predictors of torsades de pointes induced by almokalant infusion in patients with chronic atrial fibrillation or flutter: a prospective study.

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The Diagnostic Performance of Computer Programs for the Interpretation of Electrocardiograms

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Lack of effect of reboxetine on cardiac repolarization

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Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

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Estimation of potency of HERG channel blockers: impact of voltage protocol and temperature

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Co-administration of ketoconazole with H1-antagonists ebastine and loratadine in healthy subjects: pharmacokinetic and pharmacodynamic effects

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Comparing methods of measurement for detecting drug-induced changes in the QT interval: implications for thoroughly conducted ECG studies.

21 January 2018

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Comparative accuracy of manual versus computerized electrocardiographic measurement of J-, ST- and T-wave deviations in patients with acute coronary syndrome.

21 January 2018

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Diagnostic accuracy of screening electrocardiograms in long QT syndrome I.

21 January 2018

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Electrocardiographic changes in children and adolescents treated with ziprasidone: a prospective study

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21 January 2018

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Within-subject electrocardiographic differences at equal heart rates: role of the autonomic nervous system

21 January 2018

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Exaggerated QT prolongation after cardioversion of atrial fibrillation

21 January 2018

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Comparison of QT dispersion during atrial fibrillation and sinus rhythm in the same patients, at normal and prolonged ventricular repolarization

21 January 2018

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Taking the "idio" out of "idiosyncratic": predicting torsades de pointes

21 January 2018

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Computer-based analysis of dynamic QT changes: toward high precision and individual rate correction

21 January 2018

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The effect of terfenadine on the cardiac pharmacodynamics of sparfloxacin

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/0091270006286900

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14 January 2018

PubMed ID

16707406

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14 January 2018