(Q47344343)

14 January 2018

title

RNA aptamer to thrombin binds anion-binding exosite-2 and alters protease inhibition by heparin-binding serpins (English)

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14 January 2018

author name string

Martha L Jeter

1

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14 January 2018

Linda V Ly

2

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14 January 2018

Yolanda M Fortenberry

3

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14 January 2018

Herbert C Whinna

4

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14 January 2018

Rebekah R White

5

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14 January 2018

Christopher P Rusconi

6

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14 January 2018

Bruce A Sullenger

7

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14 January 2018

Frank C Church

8

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14 January 2018

language of work or name

English

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publication date

1 June 2004

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14 January 2018

published in

FEBS Letters

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14 January 2018

volume

568

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14 January 2018

issue

1-3

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14 January 2018

page(s)

10-14

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14 January 2018

cites work

The Protein C Pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Serpin structure, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Beyond heparin and aspirin: new treatments for unstable angina and non-Q-wave myocardial infarction

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

The coagulation cascade: initiation, maintenance, and regulation

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Developing aptamers into therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

High-affinity RNA ligands to human alpha-thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Generation of species cross-reactive aptamers using "toggle" SELEX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

RNA aptamers as reversible antagonists of coagulation factor IXa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Thrombin interacts with thrombomodulin, protein C, and thrombin-activatable fibrinolysis inhibitor via specific and distinct domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

The anticoagulant effect of heparan sulfate and dermatan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Aspartic acid residues 72 and 75 and tyrosine-sulfate 73 of heparin cofactor II promote intramolecular interactions during glycosaminoglycan binding and thrombin inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Oligonucleotide inhibitors of human thrombin that bind distinct epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

An extensive interaction interface between thrombin and factor V is required for factor V activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Molecular mapping of the heparin-binding exosite of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Comparison of heparin- and dermatan sulfate-mediated catalysis of thrombin inactivation by heparin cofactor II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

The conformational activation of antithrombin. A 2.85-A structure of a fluorescein derivative reveals an electrostatic link between the hinge and heparin binding regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Inhibition of a thrombin anion-binding exosite-2 mutant by the glycosaminoglycan-dependent serpins protein C inhibitor and heparin cofactor II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Anticoagulant activities of a monoclonal antibody that binds to exosite II of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

The discovery and characterization of a novel nucleotide-based thrombin inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

Effect of oligodeoxynucleotide thrombin aptamer on thrombin inhibition by heparin cofactor II and antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.04.087

10.1016/J.FEBSLET.2004.04.087

21 January 2018

Identifiers

DOI

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14 January 2018

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14 January 2018