(Q47349068)

14 January 2018

title

Absence of p21WAF1 cooperates with c-myc in bypassing Ras-induced senescence and enhances oncogenic cooperation (English)

1 reference

14 January 2018

1 reference

Amancio Carnero

1

0 references

author name string

David H Beach

series ordinal

2

1 reference

14 January 2018

language of work or name

English

0 references

publication date

1 August 2004

1 reference

14 January 2018

published in

Oncogene

1 reference

14 January 2018

volume

23

1 reference

14 January 2018

issue

35

1 reference

14 January 2018

page(s)

6006-6011

1 reference

14 January 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1207839

exact match

0 references

cites work

Myc and the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Cooperation between oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Differential modulation of cyclin gene expression by MYC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Ras/MEK signaling suppresses Myc-dependent apoptosis in cells transformed by c-myc and activated ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

The multistep nature of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Senescence of human fibroblasts induced by oncogenic Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

7 January 2021

Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

7 January 2021

Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

7 January 2021

Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207839

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207839

1 reference

14 January 2018

PubMed ID

15195145

1 reference

14 January 2018