(Q47394478)

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Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

scientific article published on 8 April 2015

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Europe PubMed Central

PubMed publication ID

15 January 2018

http://europepmc.org/abstract/MED/25863193

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence (English)

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Europe PubMed Central

PubMed publication ID

15 January 2018

http://europepmc.org/abstract/MED/25863193

adverse outcome pathway

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Helmut Segner

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PubMed publication ID

15 January 2018

Gerald T Ankley

2

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Gerald T Ankley

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Europe PubMed Central

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Daniel L Villeneuve

10

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Daniel L Villeneuve

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Stephen Edwards

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Stephen W Edwards

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15 January 2018

http://europepmc.org/abstract/MED/25863193

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Richard A Becker

1

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Sean W Kennedy

4

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Europe PubMed Central

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Igor Linkov

5

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Bette Meek

6

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Magdalini Sachana

7

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Bart Van Der Burg

9

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Europe PubMed Central

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Haruna Watanabe

11

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Europe PubMed Central

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Tara S Barton-Maclaren

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15 January 2018

http://europepmc.org/abstract/MED/25863193

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8 April 2015

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Europe PubMed Central

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15 January 2018

http://europepmc.org/abstract/MED/25863193

Regulatory Toxicology and Pharmacology

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15 January 2018

http://europepmc.org/abstract/MED/25863193

72

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15 January 2018

http://europepmc.org/abstract/MED/25863193

3

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Europe PubMed Central

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15 January 2018

http://europepmc.org/abstract/MED/25863193

514-537

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Europe PubMed Central

PubMed publication ID

15 January 2018

http://europepmc.org/abstract/MED/25863193

Evaluation of the aromatase inhibitor fadrozole in a short-term reproduction assay with the fathead minnow (Pimephales promelas).

1 reference

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Effects of two fungicides with multiple modes of action on reproductive endocrine function in the fathead minnow (Pimephales promelas).

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7 January 2021

The fathead minnow in aquatic toxicology: past, present and future

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7 January 2021

Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action.

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7 January 2021

Dynamic nature of alterations in the endocrine system of fathead minnows exposed to the fungicide prochloraz

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7 January 2021

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

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7 January 2021

Temporal changes in biological responses and uncertainty in assessing risks of endocrine-disrupting chemicals: insights from intensive time-course studies with fish

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7 January 2021

Species extrapolation for the 21st century.

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7 January 2021

Meeting the common needs of a more effective and efficient testing and assessment paradigm for chemical risk management.

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7 January 2021

Developing scientific confidence in HTS-derived prediction models: lessons learned from an endocrine case study.

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7 January 2021

Are adverse outcome pathways here to stay?

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7 January 2021

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology.

1 reference

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7 January 2021

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish

1 reference

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7 January 2021

Tools for the prioritization of substances on the Domestic Substances List in Canada on the basis of hazard.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2015.04.004

7 January 2021

Collapse of a fish population after exposure to a synthetic estrogen.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2015.04.004

7 January 2021

Adverse outcome pathways and ecological risk assessment: Bridging to population‐level effects

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2015.04.004

7 January 2021

Weight-of-evidence evaluation in environmental assessment: review of qualitative and quantitative approaches

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7 January 2021

Proposed mode of action of benzene-induced leukemia: Interpreting available data and identifying critical data gaps for risk assessment.

1 reference

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7 January 2021

New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis.

1 reference

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7 January 2021

Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence

1 reference

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7 January 2021

Modeling impacts on populations: fathead minnow (Pimephales promelas) exposure to the endocrine disruptor 17beta-trenbolone as a case study

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7 January 2021

A decision analytic approach to exposure-based chemical prioritization

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7 January 2021

Combined effects of oestrogen receptor antagonists on in vitro vitellogenesis

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7 January 2021

Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals.

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7 January 2021

A survey of frameworks for best practices in weight-of-evidence analyses

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7 January 2021

Propiconazole inhibits steroidogenesis and reproduction in the fathead minnow (Pimephales promelas).

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7 January 2021

Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment

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7 January 2021

Screening of chemicals with anti-estrogenic activity using in vitro and in vivo vitellogenin induction responses in zebrafish (Danio rerio).

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7 January 2021

Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor

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7 January 2021

Adverse outcome pathway (AOP) development I: strategies and principles

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7 January 2021

Adverse outcome pathway development II: best practices.

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7 January 2021

Weight of evidence: a review of concept and methods

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Development of the adverse outcome pathway "alkylation of DNA in male premeiotic germ cells leading to heritable mutations" using the OECD's users' handbook supplement.

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Endocrine disruption and reproduction impairment in zebrafish after long-term exposure to DE-71.

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7 January 2021

Identifiers

10.1016/J.YRTPH.2015.04.004

1 reference

Europe PubMed Central

PubMed publication ID

15 January 2018

http://europepmc.org/abstract/MED/25863193

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 January 2018

http://europepmc.org/abstract/MED/25863193

ResearchGate publication ID

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