(Q47405344)

15 January 2018

title

Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer (English)

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15 January 2018

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7

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15 January 2018

Jagat R Kanwar

6

object named as

Jagat R Kanwar

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15 January 2018

author name string

Lixin Ma

1

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15 January 2018

Haiquan Qiao

2

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15 January 2018

Changjun He

3

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15 January 2018

Qian Yang

4

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15 January 2018

Chun Hei Antonio Cheung

5

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15 January 2018

publication date

16 November 2010

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15 January 2018

Investigational New Drugs

published in

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15 January 2018

volume

30

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15 January 2018

issue

2

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15 January 2018

page(s)

508-517

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15 January 2018

cites work

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The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases

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Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4.

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Roles of chemokine receptor 4 (CXCR4) and chemokine ligand 12 (CXCL12) in metastasis of hepatocellular carcinoma cells

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Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion.

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Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival.

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Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients

21 January 2018

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Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human colorectal cancer.

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The biological relevance of chemokine-proteoglycan interactions

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Therapeutic use of heparin beyond anticoagulation

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P-selectin- and heparanase-dependent antimetastatic activity of non-anticoagulant heparins

21 January 2018

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Mechanisms of heparin induced anti-cancer activity in experimental cancer models

21 January 2018

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Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids?

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Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo

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Interaction of SDF-1alpha and CXCR4 plays an important role in pulmonary cellular infiltration in differentiation syndrome

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Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells

21 January 2018

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Long-term expression of angiostatin suppresses metastatic liver cancer in mice

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Overexpression of von Hippel-Lindau tumor suppressor protein and antisense HIF-1alpha eradicates gliomas

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Regional expression of CXCL12/CXCR4 in liver and hepatocellular carcinoma and cell-cycle variation during in vitro differentiation

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Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis.

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CXCR4 regulates the early extravasation of metastatic tumor cells in vivo

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CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

21 January 2018

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 January 2018

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Role of chemokines in tumor growth

21 January 2018

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Characterization of the stromal cell-derived factor-1alpha-heparin complex

21 January 2018

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Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1 ) Binding to Heparin

21 January 2018

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The monomer-dimer equilibrium of stromal cell-derived factor-1 (CXCL 12) is altered by pH, phosphate, sulfate, and heparin

21 January 2018

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Heparin octasaccharides inhibit angiogenesis in vivo.

21 January 2018

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Cancer cell dissemination during curative surgery for colorectal liver metastases.

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Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells

21 January 2018

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12 December 2020

Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression

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12 December 2020

Downregulation of developmentally regulated endothelial cell locus-1 inhibits the growth of colon cancer

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12 December 2020

The potential benefits of low-molecular-weight heparins in cancer patients

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12 December 2020

A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factor-1, in the development of bone marrow metastases in neuroblastoma

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12 December 2020

Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells

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12 December 2020

Current management of colorectal hepatic metastasis

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12 December 2020

The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases

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12 December 2020

Anti-metastatic activity of heparin is probably associated with modulation of SDF-1-CXCR4 axis

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12 December 2020

Immunohistochemical expression of stromal cell-derived factor-1 (SDF-1) and CXCR4 ligand receptor system in hepatocellular carcinoma

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12 December 2020

Stromal Cell–Derived Factor-1 from Biliary Epithelial Cells Recruits CXCR4-Positive Cells: Implications for Inflammatory Liver Diseases

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12 December 2020

Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone

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12 December 2020

10.1007/S10637-010-9578-0

Identifiers

DOI

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15 January 2018

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15 January 2018