(Q47418397)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

The elusive role of the potential factor X cation-binding exosite-1 in substrate and inhibitor interactions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

coagulation factor x human

20 December 2019

main subject

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Robert N. Pike

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Bernard Le Bonniec

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

author name string

Elsa P Bianchini

series ordinal

1

1 reference

16 January 2018

http://europepmc.org/abstract/MED/14583605

language of work or name

English

0 references

publication date

28 October 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

20 December 2019

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

page(s)

3671-3679

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

Single amino acid substitutions dissociate fibrinogen-clotting and thrombomodulin-binding activities of human thrombin

20 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Molecular mapping of the heparin-binding exosite of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor VIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Peptide exosite inhibitors of factor VIIa as anticoagulants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Surface loop 199-204 in blood coagulation factor IX is a cofactor-dependent site involved in macromolecular substrate interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Structural mechanism for heparin-binding of the third Kunitz domain of human tissue factor pathway inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Mapping of the catalytic groove preferences of factor Xa reveals an inadequate selectivity for its macromolecule substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

The stratagem utilized by the plasminogen activator from the snake Trimeresurus stejnegeri to escape serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Enhanced gamma-carboxylation of recombinant factor X using a chimeric construct containing the prothrombin propeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Activation of factor X: kinetic properties of the reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

17 The kinetics of reversible tight-binding inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Studies on synthetic peptides that bind to fibrinogen and prevent fibrin polymerization. Structural requirements, number of binding sites, and species differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Prevention of the influence of fibrin and alpha2-macroglobulin in the continuous measurement of the thrombin potential: implications for an endpoint determination of the optical density.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Macromolecular substrate affinity for the tissue factor-factor VIIa complex is independent of scissile bond docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Proexosite-1 on Prothrombin Is a Factor Va-dependent Recognition Site for the Prothrombinase Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Kinetics of the inhibition of thrombin by hirudin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Probing the molecular basis of factor Xa specificity by mutagenesis of the serpin, antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Definition of a factor Va binding site in factor Xa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Mechanism of heparin activation of antithrombin. Evidence for reactive center loop preinsertion with expulsion upon heparin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Calcium enhances heparin catalysis of the antithrombin-factor Xa reaction by promoting the assembly of an intermediate heparin-antithrombin-factor Xa bridging complex. Demonstration by rapid kinetics studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Heparin activates antithrombin anticoagulant function by generating new interaction sites (exosites) for blood clotting proteinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Molecular determinants of the mechanism underlying acceleration of the interaction between antithrombin and factor Xa by heparin pentasaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Role of basic residues of the autolysis loop in the catalytic function of factor Xa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Serpin-resistant mutants of human tissue-type plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Identification of basic residues in the heparin-binding exosite of factor Xa critical for heparin and factor Va binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Exosites determine macromolecular substrate recognition by prothrombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Regions remote from the site of cleavage determine macromolecular substrate recognition by the prothrombinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

The contribution of factor Xa to exosite-dependent substrate recognition by prothrombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Topology of the stable serpin-protease complexes revealed by an autoantibody that fails to react with the monomeric conformers of antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

The propeptides of the vitamin K-dependent proteins possess different affinities for the vitamin K-dependent carboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Regulation of plasminogen activator secretion in mouse peritoneal macrophages. I. - Role of serum studied by a new spectrophotometric assay for plasminogen activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Role of the P2 residue in determining the specificity of serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Interaction of calcium with native and decarboxylated human factor X. Effect of proteolysis in the autolysis loop on catalytic efficiency and factor Va binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Interaction of factor IXa with factor VIIIa. Effects of protease domain Ca2+ binding site, proteolysis in the autolysis loop, phospholipid, and factor X

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Demonstration of exosite I-dependent interactions of thrombin with human factor V and factor Va involving the factor Va heavy chain: analysis by affinity chromatography employing a novel method for active-site-selective immobilization of serine prot

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Role of proexosite I in factor Va-dependent substrate interactions of prothrombin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Exosite binding tethers the macromolecular substrate to the prothrombinase complex and directs cleavage at two spatially distinct sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Substitution of asparagine for arginine 347 of recombinant factor Xa markedly reduces factor Va binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Identification of a binding site for blood coagulation factor Xa on the heavy chain of factor Va. Amino acid residues 323-331 of factor V represent an interactive site for activated factor X

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Role of thrombin anion-binding exosite-I in the formation of thrombin-serpin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

Localization of the heparin binding exosite of factor IXa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309691200

21 January 2018

Identifiers

DOI

10.1074/JBC.M309691200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14583605%20AND%20SRC:MED&resulttype=core&format=json

release_di6ty5oqt5fdbgrgtofkdtjm34

20 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/di6ty5oqt5fdbgrgtofkdtjm34

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference