(Q43941686)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11925440%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Mapping of the catalytic groove preferences of factor Xa reveals an inadequate selectivity for its macromolecule substrates (English)

1 reference

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8 December 2019

1 reference

1

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8 December 2019

Bernard Le Bonniec

6

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8 December 2019

author name string

Virginie B Louvain

2

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8 December 2019

Pierre-Emmanuel Marque

3

1 reference

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8 December 2019

Maria A Juliano

4

1 reference

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8 December 2019

Luiz Juliano

5

1 reference

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8 December 2019

language of work or name

English

0 references

publication date

29 March 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11925440%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

8 December 2019

published in

1 reference

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8 December 2019

volume

277

1 reference

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8 December 2019

issue

23

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8 December 2019

page(s)

20527-20534

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The coagulation cascade: initiation, maintenance, and regulation

8 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Structure of human des(1-45) factor Xa at 2.2 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Thrombin signalling and protease-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

The interaction of thrombin with fibrinogen. A structural basis for its specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Cofactor proteins in the assembly and expression of blood clotting enzyme complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Cloning and expression in COS-1 cells of a full-length cDNA encoding human coagulation factor X.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

The activation of bovine coagulation factor X

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Residue 225 determines the Na(+)-induced allosteric regulation of catalytic activity in serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

28 Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Mapping the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: development of new sensitive substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Active-site mapping of bovine and human blood coagulation serine proteases using synthetic peptide 4-nitroanilide and thio ester substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Substrate phage: selection of protease substrates by monovalent phage display

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Reactivity of bovine blood coagulation factor IXa beta, factor Xa beta, and factor XIa toward fluorogenic peptides containing the activation site sequences of bovine factor IX and factor X.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Mapping the S' subsites of serine proteases using acyl transfer to mixtures of peptide nucleophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Role of the S' subsites in serine protease catalysis. Active-site mapping of rat chymotrypsin, rat trypsin, alpha-lytic protease, and cercarial protease from Schistosoma mansoni.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

S' subsite mapping of serine proteases based on fluorescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Probing the molecular basis of factor Xa specificity by mutagenesis of the serpin, antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Mapping the active site of factor Xa by selective inhibitors: an NMR and MD study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Regulation of extrinsic pathway factor Xa formation by tissue factor pathway inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Subunit structure and function of porcine factor Xa-activated factor VIII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Human protein S cleavage and inactivation by coagulation factor Xa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Characterization of the P2' and P3' specificities of thrombin using fluorescence-quenched substrates and mapping of the subsites by mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

The role of Glu(192) in the allosteric control of the S(2)' and S(3)' subsites of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

The action of factor Xa on peptide p-nitroanilide substrates: substrate selectivity and examination of hydrolysis with different reaction conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human coagulation factor xa. Studies on catalytic efficiency and inhibitor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Highly sensitive peptide-4-methylcoumaryl-7-amide substrates for blood-clotting proteases and trypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Refined 2 A X-ray crystal structure of porcine pancreatic kallikrein A, a specific trypsin-like serine proteinase. Crystallization, structure determination, crystallographic refinement, structure and its comparison with bovine trypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Engineering the S1' subsite of trypsin: design of a protease which cleaves between dibasic residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Exosites determine macromolecular substrate recognition by prothrombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Regions remote from the site of cleavage determine macromolecular substrate recognition by the prothrombinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

Exosite binding tethers the macromolecular substrate to the prothrombinase complex and directs cleavage at two spatially distinct sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201139200

21 January 2018

Identifiers

DOI

10.1074/JBC.M201139200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11925440%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference