(Q41810631)

English

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants

scientific article published on November 1997

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scholarly article

1 reference

Europe PubMed Central

12 October 2017

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants (English)

1 reference

Europe PubMed Central

12 October 2017

Karl-Peter Hopfner

1

1 reference

Europe PubMed Central

12 October 2017

Hans Brandstetter

2

1 reference

Europe PubMed Central

12 October 2017

author name string

Karcher A

3

1 reference

Europe PubMed Central

12 October 2017

Kopetzki E

4

1 reference

Europe PubMed Central

12 October 2017

Huber R

5

1 reference

Europe PubMed Central

12 October 2017

Engh RA

6

1 reference

Europe PubMed Central

12 October 2017

Bode W

7

1 reference

Europe PubMed Central

12 October 2017

language of work or name

0 references

publication date

1 November 1997

1 reference

Europe PubMed Central

12 October 2017

The EMBO Journal

1 reference

Europe PubMed Central

12 October 2017

16

1 reference

Europe PubMed Central

12 October 2017

6626-6635

1 reference

Europe PubMed Central

12 October 2017

22

1 reference

Europe PubMed Central

12 October 2017

The 2.8 A crystal structure of Gla-domainless activated protein C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Trypsin: a case study in the structural determinants of enzyme specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Role of residue 99 at the S2 subsite of factor Xa and activated protein C in enzyme specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Analysis of the functions of the first epidermal growth factor-like domain of factor X.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Structure of human des(1-45) factor Xa at 2.2 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Structural basis of substrate specificity in the serine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Conversion of thrombin into an anticoagulant by protein engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Mapping the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: development of new sensitive substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Isolation and characterization of a cDNA coding for human factor IX

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Reactivity of bovine blood coagulation factor IXa beta, factor Xa beta, and factor XIa toward fluorogenic peptides containing the activation site sequences of bovine factor IX and factor X.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

28 Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Activation of human prothrombin by human prothrombinase. Influence of factor Va on the reaction mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

The molecular basis of blood coagulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

ompT encodes the Escherichia coli outer membrane protease that cleaves T7 RNA polymerase during purification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

High-level expression of recombinant genes in Escherichia coli is dependent on the availability of the dnaY gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Factor IX New London: substitution of proline for glutamine at position 50 causes severe hemophilia B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Additivity of mutational effects in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Cooperative activation of human factor IX by the human extrinsic pathway of blood coagulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

The coagulation cascade: initiation, maintenance, and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Converting trypsin to chymotrypsin: the role of surface loops

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Coagulant protein of Russell's viper venom

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Activation of human factor IX (Christmas factor)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Activation of bovine factor IX (Christmas factor) by factor XIa (activated plasma thromboplastin antecedent) and a protease from Russell's viper venom

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

6 June 2018

Active-site mapping of bovine and human blood coagulation serine proteases using synthetic peptide 4-nitroanilide and thio ester substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170267

18 August 2018

Mechanism of activation of bovine factor IX (Christmas factor) by bovine factor XIa(activated plasma thromboplastin antecedent)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood coagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of phospholipid and factor VIIIa in the activation of bovine factor X

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rational engineering of activity and specificity in a serine protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STUDIES ON THE ACTIVE CENTER OF TRYPSIN. THE BINDING OF AMIDINES AND GUANIDINES AS MODELS OF THE SUBSTRATE SIDE CHAIN

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Simplified Procedure for Purification of Human Prothrombin, Factor IX and Factor X

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrinsic pathway activation of factor X and its activation peptide-deficient derivative, factor Xdes-143-191

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biology of hemophilia B

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Converting trypsin to chymotrypsin: residue 172 is a substrate specificity determinant

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-range, small magnitude nonadditivity of mutational effects in proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage at arginine 145 in human blood coagulation factor IX converts the zymogen into a factor VIII binding enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9362477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/16.22.6626

1 reference

Europe PubMed Central

12 October 2017

1 reference

Europe PubMed Central

12 October 2017

1 reference

Europe PubMed Central

12 October 2017

ResearchGate publication ID

0 references

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