(Q47445868)

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The anti-proliferative side effects of AEE788, a tyrosine kinase inhibitor blocking both EGF- and VEGF-receptor, are liver-size-dependent after partial hepatectomy in rats

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

The anti-proliferative side effects of AEE788, a tyrosine kinase inhibitor blocking both EGF- and VEGF-receptor, are liver-size-dependent after partial hepatectomy in rats (English)

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

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Uta Dahmen

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

author name string

Meihong Deng

1

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

Hai Huang

2

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

Hao Jin

3

1 reference

Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

Olaf Dirsch

4

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

publication date

12 February 2010

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

Investigational New Drugs

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

29

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

4

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

593-606

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Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

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Novel therapeutic developments other than EGFR and VEGF inhibition in colorectal cancer

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EGFR-targeted therapies in colorectal cancer

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Effect of molecular therapeutics on liver regeneration in a murine model.

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AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity

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Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy.

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Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model

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Targeting receptor tyrosine kinase on lymphatic endothelial cells for the therapy of colon cancer lymph node metastasis

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Antitumor activity of imatinib mesylate in neuroblastoma xenografts

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Statistical and economical efficiency in assessment of liver regeneration using defined sample size and selection in combination with a fully automated image analysis system

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Altered regulation of EGF receptor signaling following a partial hepatectomy

1 reference

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The kinetics of cellular proliferation in regenerating liver

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Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer

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Tumor cell and endothelial cell therapy of oral cancer by dual tyrosine kinase receptor blockade

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Novel targeted approaches to treating biliary tract cancer: the dual epidermal growth factor receptor and ErbB-2 tyrosine kinase inhibitor NVP-AEE788 is more efficient than the epidermal growth factor receptor inhibitors gefitinib and erlotinib

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Epidermal growth factor receptor inhibitors in development for the treatment of non-small cell lung cancer

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Hepatic transport of PKI166, an epidermal growth factor receptor kinase inhibitor of the pyrrolo-pyrimidine class, and its main metabolite, ACU154.

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Liver failure after partial hepatic resection: definition, pathophysiology, risk factors and treatment

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Combined inhibition of the VEGFR and EGFR signaling pathways in the treatment of NSCLC.

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A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: evidence of gene expression, cellular, and clinical response

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Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: safety, pharmacokinetics, and pharmacodynamics

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Insights into the pathophysiology and management of dermatologic toxicities to EGFR-targeted therapies in colorectal cancer.

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The role of growth factors in gastrointestinal cell proliferation

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21 January 2018

Clinicopathological features and prognosis in resectable synchronous and metachronous colorectal liver metastasis

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect and risk of AEE788, a dual tyrosine kinase inhibitor, on regeneration in a rat liver resection model

1 reference

https://pubmed.ncbi.nlm.nih.gov/20148349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I study of sorafenib in Japanese patients with hepatocellular carcinoma

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy of multidrug resistant human prostate tumors in the prostate of nude mice by simultaneous targeting of the epidermal growth factor receptor and vascular endothelial growth factor receptor on tumor-associated endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20148349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marginal hepatectomy in the rat: from anatomy to surgery

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative evaluation and selection of reference genes in a rat model of extended liver resection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20148349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic resection for colorectal metastases: value for risk scoring systems?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20148349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nodular regenerative hyperplasia in partial hepatectomy specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/20148349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dual EGF/VEGF receptor tyrosine kinase inhibitor AEE788 inhibits growth of human hepatocellular carcinoma xenografts in nude mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20148349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool

1 reference

https://pubmed.ncbi.nlm.nih.gov/20148349

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10637-010-9394-6

1 reference

Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 January 2018

http://europepmc.org/abstract/MED/20148349

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