(Q47448991)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Scalable syntheses of both enantiomers of DNJNAc and DGJNAc from glucuronolactone: the effect of N-alkylation on hexosaminidase inhibition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Atsushi Kato

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Benjamin Ayers

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Matilde Aguilar-Moncayo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

José Manuel García Fernández

6 February 2020

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

author name string

Andreas F G Glawar

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Daniel Best

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Saori Miyauchi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Shinpei Nakagawa

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Elizabeth V Crabtree

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Terry D Butters

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Francis X Wilson

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

George W J Fleet

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

language of work or name

English

0 references

publication date

26 June 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

Chemistry—A European Journal

6 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

page(s)

9341-9359

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22736508%20AND%20SRC:MED&resulttype=core&format=json

Sugar-mimicking glycosidase inhibitors: bioactivity and application

6 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Amino-sugar glycosidase inhibitors: versatile tools for glycobiologists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Polyhydroxylated alkaloids -- natural occurrence and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Pochonicine, a polyhydroxylated pyrrolizidine alkaloid from fungus Pochonia suchlasporia var. suchlasporia TAMA 87 as a potent beta-N-acetylglucosaminidase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

GlcNAc-Thiazoline conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

NAG-thiazoline, An N -Acetyl-β-hexosaminidase Inhibitor That Implicates Acetamido Participation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Synthesis, evaluation, and mechanism of N,N,N-trimethyl-D-glucosamine-(1→4)-chitooligosaccharides as selective inhibitors of glycosyl hydrolase family 20 β-N-acetyl-D-hexosaminidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Sphingolipid metabolism diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Design, synthesis, and biological evaluation of enantiomeric beta-N-acetylhexosaminidase inhibitors LABNAc and DABNAc as potential agents against Tay-Sachs and Sandhoff disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Synthesis and high-throughput screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Chitin induces accumulation in tissue of innate immune cells associated with allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Inhibition of O-GlcNAcase in perfused rat hearts by NAG-thiazolines at the time of reperfusion is cardioprotective in an O-GlcNAc-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

β-N-acetylhexosaminidase: what's in a name…?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Interconversion of the Specificities of Human Lysosomal Enzymes Associated with Fabry and Schindler Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Catalytic mechanism of human alpha-galactosidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler and Kanzaki diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Three dimensional structural studies of alpha-N-acetylgalactosaminidase (alpha-NAGA) in alpha-NAGA deficiency (Kanzaki disease): different gene mutations cause peculiar structural changes in alpha-NAGAs resulting in different substrate specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Lysosomal storage disorders in the newborn

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Defects in degradation of blood group A and B glycosphingolipids in Schindler and Fabry diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Serum proteomic profile of cutaneous malignant melanoma and relation to cancer progression: association to tumor derived alpha-N-acetylgalactosaminidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Inhibition of tumor metastasis in vivo by combination of paclitaxel and hyaluronic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Mechanistic investigation of the endo-alpha-N-acetylgalactosaminidase from Streptococcus pneumoniae R6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Crystallographic and mutational analyses of substrate recognition of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Identification of a pneumococcal glycosidase that modifies O-linked glycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Molecular cloning, expression, and characterization of a novel endo-alpha-N-acetylgalactosaminidase from Enterococcus faecalis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Novel endo-alpha-N-acetylgalactosaminidases with broader substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Characterization of two different endo-alpha-N-acetylgalactosaminidases from probiotic and pathogenic enterobacteria, Bifidobacterium longum and Clostridium perfringens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

The chemistry of the 1-deoxynojirimycin system. Synthesis of 2-acetamido-1,2-dideoxynojirimycin from 1-deoxynojirimycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

2-Acetamino-1,2-dideoxynojirimycin-lysine hybrids as hexosaminidase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Synthesis and evaluation of calystegine B2 analogues as glycosidase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Synthesis and biological evaluation of guanidine-type iminosugars.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Glycomimetics at the mirror: medicinal chemistry of L-iminosugars.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Chiral toxicology: it's the same thing...only different

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

4-C-Me-DAB and 4-C-Me-LAB - enantiomeric alkyl-branched pyrrolidine iminosugars - are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Chemical and chemoenzymatic synthesis of glycosyl-amino acids and glycopeptides related to Trypanosoma cruzi mucins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Activity of lysosomal exoglycosidases in human gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Cellular effects of deoxynojirimycin analogues: uptake, retention and inhibition of glycosphingolipid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Pharmacokinetics, safety and tolerability of miglustat in the treatment of pediatric patients with GM2 gangliosidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110

Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201200110