(Q47565961)

4 February 2018

title

Immune aspects of sepsis and hope for new therapeutics (English)

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4 February 2018

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Steven P Larosa

1

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4 February 2018

Steven M Opal

series ordinal

2

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4 February 2018

publication date

1 October 2012

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4 February 2018

Current infectious disease reports

published in

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4 February 2018

volume

14

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4 February 2018

issue

5

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4 February 2018

page(s)

474-483

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4 February 2018

Host-pathogen interactions in sepsis

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Molecular biology of inflammation and sepsis: a primer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Th17 and regulatory T cells in mediating and restraining inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Inferences, questions and possibilities in Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Inhibition of bacterial superantigens by peptides and antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Binding of superantigen toxins into the CD28 homodimer interface is essential for induction of cytokine genes that mediate lethal shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Coagulation abnormalities in critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Thrombin signalling and protease-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Copy number variation and susceptibility to complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

The pathophysiology and treatment of sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

The sepsis seesaw: tilting toward immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Apoptosis and caspases regulate death and inflammation in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Immunotherapy for sepsis--a new approach against an ancient foe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Immunosuppression in patients who die of sepsis and multiple organ failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

TLR-mediated B cell activation results in ectopic CLIP expression that promotes B cell-dependent inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Nonresolving inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

T cells are potent early mediators of the host response to sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Resolution of inflammation: the beginning programs the end

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Resolvin E1 and protectin D1 activate inflammation-resolution programmes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Functional innervation of hepatic iNKT cells is immunosuppressive following stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

The inflammasomes: guardians of the body

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Protection against an Escherichia coli-induced sepsis by alkaline phosphatase in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Bovine intestinal alkaline phosphatase attenuates the inflammatory response in secondary peritonitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Alkaline phosphatase treatment improves renal function in severe sepsis or septic shock patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

AB103, a CD28 antagonist peptide: a new therapeutic agent in a model of severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Peroxisome proliferator-activated receptor-gamma is a new therapeutic target in sepsis and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Peroxisome proliferator-activated receptor-gamma antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Changes in peroxisome proliferator-activated receptor-gamma activity in children with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Drotrecogin alfa (activated) in adults with septic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Therapeutic potential of targeting the complement cascade in critical care medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Role of C5a-C5aR interaction in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Pathophysiology, staging and therapy of severe sepsis in baboon models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Protective effects of C5a blockade in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

C1-esterase inhibitor infusion increases survival rates for patients with sepsis*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Improved survival in experimental sepsis with an orally administered inhibitor of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

PyNTTTTGT prototype oligonucleotide IMT504, a novel effective adjuvant of the FMDV DNA vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Pharmacological characterization of FE 202158, a novel, potent, selective, and short-acting peptidic vasopressin V1a receptor full agonist for the treatment of vasodilatory hypotension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Stem cells in sepsis and acute lung injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11908-012-0276-2

Dephosphorylation of endotoxin by alkaline phosphatase in vivo.

21 January 2018

1 reference

12 December 2020

Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation

1 reference

12 December 2020

Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis

1 reference

12 December 2020

Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial

1 reference

12 December 2020

The inhibitory effect of recombinant human soluble thrombomodulin on initiation and extension of coagulation--a comparison with other anticoagulants

1 reference

12 December 2020

A matrix metalloprotease-PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis.

1 reference

12 December 2020

Safety and efficacy of affinity-purified, anti–tumor necrosis factor-α, ovine fab for injection (CytoFab) in severe sepsis*

1 reference

12 December 2020

Immunodeficiency and genetic defects of pattern-recognition receptors

1 reference

12 December 2020

IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis.

1 reference

12 December 2020

Affinity apheresis for treatment of bacteremia caused by Staphylococcus aureus and/or methicillin-resistant S. aureus (MRSA).

1 reference

12 December 2020

Innate response activator B cells protect against microbial sepsis.

1 reference

12 December 2020

Regulation of immune responses by T cells

1 reference

12 December 2020

10.1007/S11908-012-0276-2

Identifiers

DOI

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4 February 2018

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4 February 2018