(Q47581912)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

Molecular dissection of Na+ binding to thrombin (English)

1 reference

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28 December 2019

5

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28 December 2019

author name string

Agustin O Pineda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Christopher J Carrell

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Leslie A Bush

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Swati Prasad

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Zhi-Wei Chen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

F Scott Mathews

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Enrico Di Cera

8

1 reference

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28 December 2019

language of work or name

English

0 references

publication date

19 May 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

28 December 2019

published in

1 reference

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28 December 2019

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

issue

30

1 reference

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28 December 2019

page(s)

31842-31853

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

The dynamics of thrombin formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Role of thrombin signalling in platelets in haemostasis and thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Thrombin signalling and protease-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Thrombin and platelet activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Thrombin is a Na(+)-activated enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Redesigning the monovalent cation specificity of an enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Residue 225 determines the Na(+)-induced allosteric regulation of catalytic activity in serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Molecular markers of serine protease evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Evolution of enzyme cascades from embryonic development to blood coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Structural origins of substrate discrimination in trypsin and chymotrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Serine protease mechanism and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

The molecular environment of the Na+ binding site of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Ser(214) is crucial for substrate binding to serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

21 January 2018

Thrombin interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

An allosteric switch controls the procoagulant and anticoagulant activities of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Sodium binding site of factor Xa: role of sodium in the prothrombinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Prothrombinase assembly and S1 site occupation restore the catalytic activity of FXa impaired by mutation at the sodium-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Prothrombin Salakta: substitution of glutamic acid-466 by alanine reduces the fibrinogen clotting activity and the esterase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Gating of thrombin in platelet aggregates by pO2-linked lowering of extracellular Ca2+ concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Thermodynamics of Na+ binding to coagulation serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Crystal structure of the anticoagulant slow form of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

The thrombin epitope recognizing thrombomodulin is a highly cooperative hot spot in exosite I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Dissecting substrate recognition by thrombin using the inactive mutant S195A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Theory of allosteric effects in serine proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Valence screening of water in protein crystals reveals potential Na+ binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Experimental assessment of differences between related protein crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

A hot spot of binding energy in a hormone-receptor interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Residue Asp-189 controls both substrate binding and the monovalent cation specificity of thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Unexpected crucial role of residue 225 in serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

The interaction of thrombin with fibrinogen. A structural basis for its specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Partial characterization of vertebrate prothrombin cDNAs: amplification and sequence analysis of the B chain of thrombin from nine different species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Structure of rabbit muscle pyruvate kinase complexed with Mn2+, K+, and pyruvate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

A piston model for transmembrane signaling of the aspartate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Propagating conformational changes over long (and short) distances in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

21 January 2018

The Protein C Pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Molecular mechanisms of thrombin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Conversion of thrombin into an anticoagulant by protein engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

A thermodynamic study of the trp repressor-operator interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Cluster analysis of consensus water sites in thrombin and trypsin shows conservation between serine proteases and contributions to ligand specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Glu-192----Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Protein solvation in allosteric regulation: a water effect on hemoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Chondroitin sulfate anticoagulant activity is linked to water transfer: relevance to proteoglycan structure in atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

The molecular basis of thrombin allostery revealed by a 1.8 A structure of the "slow" form

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

Stereochemical quality of protein structure coordinates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401756200

21 January 2018

Identifiers

DOI

10.1074/JBC.M401756200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15152000%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference