(Q47590567)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

A phase 1 clinical trial of vorinostat in combination with decitabine in patients with acute myeloid leukaemia or myelodysplastic syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

main subject

phase I clinical trial

0 references

1 reference

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

author name string

Mark Kirschbaum

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Ivana Gojo

2

1 reference

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10 March 2020

Stuart L Goldberg

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Christopher Bredeson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Lisa A Kujawski

5

1 reference

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10 March 2020

Allen Yang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Peter Marks

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Paul Frankel

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Xing Sun

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Alessandra Tosolini

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Joseph E Eid

11

1 reference

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10 March 2020

Gregory M Lubiniecki

12

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10 March 2020

language of work or name

English

0 references

publication date

8 July 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Haematology

10 March 2020

published in

1 reference

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10 March 2020

volume

167

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10 March 2020

issue

2

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10 March 2020

page(s)

185-193

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia

10 March 2020

cites work

1 reference

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

21 January 2018

1 reference

Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia

21 January 2018

1 reference

Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

21 January 2018

1 reference

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

21 January 2018

1 reference

Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells

21 January 2018

1 reference

Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia

21 January 2018

1 reference

Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes

21 January 2018

1 reference

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

21 January 2018

1 reference

Phase II study of vorinostat for treatment of relapsed or refractory indolent non-Hodgkin's lymphoma and mantle cell lymphoma

21 January 2018

1 reference

Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels

21 January 2018

1 reference

A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy

21 January 2018

1 reference

Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome.

21 January 2018

1 reference

Cotreatment with the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) enhances imatinib-induced apoptosis of Bcr-Abl-positive human acute leukemia cells

21 January 2018

1 reference

Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells.

21 January 2018

1 reference

Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect

21 January 2018

1 reference

Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor

21 January 2018

1 reference

Preclinical studies of vorinostat (suberoylanilide hydroxamic acid) combined with cytosine arabinoside and etoposide for treatment of acute leukemias

21 January 2018

1 reference

Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation.

21 January 2018

1 reference

An epigenetic approach to the treatment of advanced MDS; the experience with the DNA demethylating agent 5-aza-2'-deoxycytidine (decitabine) in 177 patients

21 January 2018

1 reference

Epigenetic therapy of cancer: past, present and future

21 January 2018

1 reference

Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone 1 1Edited by J. Karn

21 January 2018

1 reference

Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/BJH.13016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25040094%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference