(Q47602559)

PubMed publication ID

29063907

4 February 2018

http://europepmc.org/abstract/MED/29063907

title

Beyond binding: antibody effector functions in infectious diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

13 May 2020

1 reference

4

Galit Alter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

13 May 2020

author name string

Lenette L Lu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

13 May 2020

Todd J Suscovich

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

13 May 2020

Sarah M Fortune

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

13 May 2020

publication date

24 October 2017

1 reference

PubMed publication ID

29063907

4 February 2018

http://europepmc.org/abstract/MED/29063907

published in

Nature Reviews Immunology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

13 May 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

13 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

13 May 2020

page(s)

46-61

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nri.2017.106

13 May 2020

exact match

0 references

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Modulation of the effector functions of a human IgG1 through engineering of its hinge region

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The influence of the hinge region length in binding of human IgG to human Fcgamma receptors

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Proteolysis of purified IgGs by human and bacterial enzymes in vitro and the detection of specific proteolytic fragments of endogenous IgG in rheumatoid synovial fluid

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Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge

21 January 2018

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Enzymatic characterization of the streptococcal endopeptidase, IdeS, reveals that it is a cysteine protease with strict specificity for IgG cleavage due to exosite binding

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Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

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Effect of mutations in the human immunoglobulin A1 (IgA1) hinge on its susceptibility to cleavage by diverse bacterial IgA1 proteases

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Fc glycans of therapeutic antibodies as critical quality attributes

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Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

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Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity

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Human antibody-Fc receptor interactions illuminated by crystal structures

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Type I and type II Fc receptors regulate innate and adaptive immunity

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Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses.

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Properties of mouse and human IgG receptors and their contribution to disease models

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Mast cells and company

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FCGR2APolymorphism Is Correlated With Clinical Outcome After Immunotherapy of Neuroblastoma With Anti-GD2 Antibody and Granulocyte Macrophage Colony-Stimulating Factor

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FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab.

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Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population

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Role of polymorphisms of toll-like receptor (TLR) 4, TLR9, toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children

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FcgammaRIIa genotype predicts progression of HIV infection.

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The Fcγ receptor IIA-H/H131 genotype is associated with bacteremia in pneumococcal community-acquired pneumonia.

21 January 2018

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Asymptomatic dengue infection in a Cuban population confirms the protective role of the RR variant of the FcgammaRIIa polymorphism

21 January 2018

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A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease

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Association of Fcγ receptor IIIa genotype with the rate of HIV infection after gp120 vaccination

21 January 2018

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High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression

21 January 2018

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Divergent immunoglobulin g subclass activity through selective Fc receptor binding

21 January 2018

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A requirement for FcγR in antibody-mediated bacterial toxin neutralization

21 January 2018

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Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo

21 January 2018

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Antibody-mediated modulation of Cryptococcus neoformans infection is dependent on distinct Fc receptor functions and IgG subclasses

21 January 2018

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Impact of immune complex size and glycosylation on IgG binding to human FcγRs

21 January 2018

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The Stoichiometry of Antibody-Mediated Neutralization and Enhancement of West Nile Virus Infection

21 January 2018

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More is not necessarily better: prozone-like effects in passive immunization with IgG.

21 January 2018

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Combination therapy with antibiotics and anthrax immune globulin intravenous (AIGIV) is potentially more effective than antibiotics alone in rabbit model of inhalational anthrax

21 January 2018

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Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity

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Passive protection against anthrax by using a high-affinity antitoxin antibody fragment lacking an Fc region

21 January 2018

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Anamnestic protective immunity to Bacillus anthracis is antibody mediated but independent of complement and Fc receptors

21 January 2018

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Analysis of the Fc gamma receptor-dependent component of neutralization measured by anthrax toxin neutralization assays

21 January 2018

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Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity

21 January 2018

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Antibody-enhanced, Fc gamma receptor-mediated endocytosis of Clostridium difficile toxin A

21 January 2018

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Evaluation of Fab and F(ab')2 fragments and isotype variants of a recombinant human monoclonal antibody against Shiga toxin 2.

21 January 2018

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Rapid evolution of the neutralizing antibody response to HIV type 1 infection

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

21 January 2018

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A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

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Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

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Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

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Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

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Structural Basis of Zika Virus-Specific Antibody Protection

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Structural basis of West Nile virus neutralization by a therapeutic antibody

21 January 2018

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Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus

21 January 2018

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Acquisition of Functional Antibodies That Block the Binding of Erythrocyte-Binding Antigen 175 and Protection Against Plasmodium falciparum Malaria in Children

21 January 2018

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Invasion-inhibitory antibodies inhibit proteolytic processing of apical membrane antigen 1 of Plasmodium falciparum merozoites

21 January 2018

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Postentry neutralization of adenovirus type 5 by an antihexon antibody

21 January 2018

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Inhibition of nuclear entry of HPV16 pseudovirus-packaged DNA by an anti-HPV16 L2 neutralizing antibody

21 January 2018

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Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore

21 January 2018

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Matrix protein-specific IgA antibody inhibits measles virus replication by intracellular neutralization

21 January 2018

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Intracellular antibody neutralizes Listeria growth

21 January 2018

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Two monoclonal antibodies with defined epitopes of P44 major surface proteins neutralize Anaplasma phagocytophilum by distinct mechanisms

21 January 2018

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Fc receptor but not complement binding is important in antibody protection against HIV.

21 January 2018

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Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner

21 January 2018

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Human antibodies to PhtD, PcpA, and Ply reduce adherence to human lung epithelial cells and murine nasopharyngeal colonization by Streptococcus pneumoniae

21 January 2018

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Antibodies to PhnD inhibit staphylococcal biofilms

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Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

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IgG in cervicovaginal mucus traps HSV and prevents vaginal herpes infections

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Direct inhibition of T-cell responses by the Cryptococcus capsular polysaccharide glucuronoxylomannan

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Human antibodies against a purified glucosylceramide from Cryptococcus neoformans inhibit cell budding and fungal growth

21 January 2018

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Complement is activated by IgG hexamers assembled at the cell surface

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Infections of People with Complement Deficiencies and Patients Who Have Undergone Splenectomy

21 January 2018

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Infections associated with the use of eculizumab: recommendations for prevention and prophylaxis

21 January 2018

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A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus

21 January 2018

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Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms

21 January 2018

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Heavily isotype-dependent protective activities of human antibodies against vaccinia virus extracellular virion antigen B5.

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Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria

21 January 2018

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CR3 (CD11b/CD18) and CR4 (CD11c/CD18) are involved in complement-independent antibody-mediated phagocytosis of Cryptococcus neoformans

21 January 2018

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Complement-Dependent Transport of Antigen into B Cell Follicles

21 January 2018

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Acquisition and presentation of follicular dendritic cell-bound antigen by lymph node-resident dendritic cells

21 January 2018

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Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells.

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Antibody response to a T-dependent antigen requires B cell expression of complement receptors

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Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

21 January 2018

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Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

21 January 2018

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Macrophages are critical effectors of antibody therapies for cancer

21 January 2018

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How immunoglobulin G antibodies kill target cells: revisiting an old paradigm

21 January 2018

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Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells

21 January 2018

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Fcgamma receptors as regulators of immune responses

21 January 2018

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Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control

21 January 2018

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Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys

21 January 2018

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Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines

21 January 2018

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Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus

21 January 2018

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Antibody-dependent cellular inhibition is associated with reduced risk against Febrile malaria in a longitudinal cohort study involving Ghanaian children

21 January 2018

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A novel antibody-dependent cellular cytotoxicity mechanism involved in defense against malaria requires costimulation of monocytes FcgammaRII and FcgammaRIII.

21 January 2018

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Fc receptor regulation of protective immunity against Chlamydia trachomatis

21 January 2018

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A Functional Role for Antibodies in Tuberculosis

21 January 2018

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High-affinity IgE receptor on eosinophils is involved in defence against parasites

21 January 2018

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Elimination of HIV-1-infected cells by broadly neutralizing antibodies

21 January 2018

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Can HIV-1-Specific ADCC Assist the Clearance of Reactivated Latently Infected Cells?

21 January 2018

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Antibody-Dependent Cellular Cytotoxicity against Reactivated HIV-1-Infected Cells

21 January 2018

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HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption

21 January 2018

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Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

21 January 2018

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Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo

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Cross-talk between TLR4 and FcgammaReceptorIII (CD16) pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Identification of a receptor required for the anti-inflammatory activity of IVIG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Cross-talk between pathogen recognizing Toll-like receptors and immunoglobulin Fc receptors in immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Signalling C-type lectin receptors, microbial recognition and immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Immune complex-induced enhancement of bacterial antigen presentation requires Fcgamma receptor III expression on dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

The function of Fcγ receptors in dendritic cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Neutrophil-Mediated Phagocytosis of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

How antibodies alter the cell entry pathway of dengue virus particles in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

A role for immune complexes in enhanced respiratory syncytial virus disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Antibody‐Dependent Enhancement, a Possible Mechanism in Augmented Pulmonary Disease of Respiratory Syncytial Virus in the Bonnet Monkey Model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Interleukin 10- and Fcgamma receptor-deficient mice resolve Leishmania mexicana lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Reversal of proinflammatory responses by ligating the macrophage Fcgamma receptor type I

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Potent neutralization of botulinum neurotoxin by recombinant oligoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Clinical care of two patients with Ebola virus disease in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Systems biology of vaccination for seasonal influenza in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Programming the magnitude and persistence of antibody responses with innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Antibodies and their receptors: different potential roles in mucosal defense.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

The movers and shapers in immune privilege of the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

The Fab and Fc fragments of IgA1 exhibit a different arrangement from that in IgG: a study by X-ray and neutron solution scattering and homology modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Long term maintenance of IgE-mediated memory in mast cells in the absence of detectable serum IgE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

A single glycan on IgE is indispensable for initiation of anaphylaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

General mechanism for modulating immunoglobulin effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

The role of constant region carbohydrate in the assembly and secretion of human IgD and IgA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Secretory component: a new role in secretory IgA-mediated immune exclusion in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Glycosylation of immunoglobulin A influences its receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Dynamics of immunoglobulins at the feto-maternal interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

A new function for platelets: IgE-dependent killing of schistosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Immunoglobulin M antibodies with ten combining sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Semi-extended solution structure of human myeloma immunoglobulin D determined by constrained X-ray scattering

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Conflicting roles of FcγRIIa H131R polymorphism in pneumonia*

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Fcgamma receptor IIIA polymorphism as a risk factor for acute poliomyelitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Valency or wählency: is the epitope diversity of the B-cell response regulated or chemically determined?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Isotype can affect the fine specificity of an antibody for a polysaccharide antigen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Monoclonal antibodies can affect complement deposition on the capsule of the pathogenic fungus Cryptococcus neoformans by both classical pathway activation and steric hindrance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

The Role and Function of Fcγ Receptors on Myeloid Cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

FcRγ-chain ITAM signaling is critically required for cross-presentation of soluble antibody-antigen complexes by dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Cell surface recycling of internalized antigen permits dendritic cell priming of B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

ENHANCEMENT OF THE INFECTIVITY OF ARBOVIRUSES BY SPECIFIC ANTISERA PRODUCED IN DOMESTIC FOWLS

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

The role of IL-10 in promoting disease progression in leishmaniasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Site-Specific Protein N- and O-Glycosylation Analysis by a C18-Porous Graphitized Carbon-Liquid Chromatography-Electrospray Ionization Mass Spectrometry Approach Using Pronase Treated Glycopeptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2017.106

Flexibility of human IgG subclasses

31 March 2020

1 reference

12 December 2020

Fc receptors as adaptive immunoreceptors

1 reference

12 December 2020

Complement System Part II: Role in Immunity

1 reference

12 December 2020

Transmembrane signaling: the joy of aggregation

1 reference

12 December 2020

Complement System Part I - Molecular Mechanisms of Activation and Regulation

1 reference

12 December 2020

Production and characterization of monoclonal antibodies to the protective antigen component of Bacillus anthracis toxin.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI.2017.106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

Dimensions Publication ID

13 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6369690&resulttype=core&format=json

13 May 2020

PubMed publication ID

29063907

1 reference