(Q47603610)

4 February 2018

title

Loss of Rassf1a enhances p53-mediated tumor predisposition and accelerates progression to aneuploidy (English)

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4 February 2018

author name string

S Tommasi

1

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4 February 2018

A Besaratinia

2

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4 February 2018

S P Wilczynski

3

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4 February 2018

G P Pfeifer

4

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4 February 2018

language of work or name

English

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publication date

4 October 2010

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4 February 2018

published in

Oncogene

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4 February 2018

volume

30

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4 February 2018

issue

6

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4 February 2018

page(s)

690-700

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4 February 2018

https://scigraph.springernature.com/pub.10.1038/onc.2010.440

exact match

0 references

cites work

Role of the Ras-association domain family 1 tumor suppressor gene in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Generating chromosome instability through the simultaneous deletion of Mad2 and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Spindle assembly checkpoint and p53 deficiencies cooperate for tumorigenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

A p53-dependent mouse spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The RASSF1A tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Guilt by association? p53 and the development of aneuploidy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Dynamics of RASSF1A/MOAP-1 association with death receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

17p (p53) allelic losses, 4N (G2/tetraploid) populations, and progression to aneuploidy in Barrett's esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Tetraploidy, aneuploidy and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The p53 tumor suppressor participates in multiple cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Tumor spectrum analysis in p53-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Characterization of the p53-dependent postmitotic checkpoint following spindle disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Control of microtubule stability by the RASSF1A tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The impact of a negligent G2/M checkpoint on genomic instability and cancer induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

p53 represses the polyploidization of primary mammary epithelial cells by activating apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The consequences of tetraploidy and aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

From polyploidy to aneuploidy, genome instability and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The pro-apoptotic Ras effector Nore1 may serve as a Ras-regulated tumor suppressor in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Genomic instability and apoptosis are frequent in p53 deficient young mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Detection of premalignant stages in cervical smears with a biotinylated probe for chromosome 1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

The centrosomal protein RAS association domain family protein 1A (RASSF1A)-binding protein 1 regulates mitotic progression by recruiting RASSF1A to spindle poles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Aneuploidy for chromosome 1 and overall DNA content in benign and malignant breast disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.440

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.440

1 reference

4 February 2018

1 reference

4 February 2018