(Q33910498)

30 July 2017

title

Generating chromosome instability through the simultaneous deletion of Mad2 and p53. (English)

1 reference

30 July 2017

Aurora A Burds

1

1 reference

30 July 2017

Annegret Schulze Lutum

series ordinal

2

1 reference

30 July 2017

Peter K Sorger

series ordinal

3

1 reference

30 July 2017

language of work or name

English

0 references

publication date

29 July 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

102

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30 July 2017

issue

32

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30 July 2017

page(s)

11296-11301

1 reference

Guilt by association? p53 and the development of aneuploidy in cancer

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Timing and checkpoints in the regulation of mitotic progression

5 July 2018

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Chromosome segregation and genomic stability

5 July 2018

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Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint".

5 July 2018

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Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

5 July 2018

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The spindle checkpoint, aneuploidy, and cancer

5 July 2018

1 reference

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Spindle checkpoint proteins and chromosome-microtubule attachment in budding yeast

5 July 2018

1 reference

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From polyploidy to aneuploidy, genome instability and cancer

5 July 2018

1 reference

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Structure, Function, and Regulation of Budding Yeast Kinetochores

5 July 2018

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Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

G1 tetraploidy checkpoint and the suppression of tumorigenesis

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

The role of chromosomal instability in tumor initiation

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Inducing precocious anaphase in cultured mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Chromosome segregation and cancer: cutting through the mystery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

The spindle checkpoint of the yeast Saccharomyces cerevisiae requires kinetochore function and maps to the CBF3 domain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Hypersensitivity to DNA damage leads to increased apoptosis during early mouse development.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Retention of the BUB3 checkpoint protein on lagging chromosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Mutations of mitotic checkpoint genes in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Characterization of the p53-dependent postmitotic checkpoint following spindle disruption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Genetic instability in colorectal cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Identification of a human mitotic checkpoint gene: hsMAD2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Checkpoint genes required to delay cell division in response to nocodazole respond to impaired kinetochore function in the yeast Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Feedback control of mitosis in budding yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Human p53 inhibits growth in Schizosaccharomyces pombe

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182134

BUBR1 deficiency results in abnormal megakaryopoiesis

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505053102

Drosophila checkpoint kinase 2 couples centrosome function and spindle assembly to genomic integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505053102

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505053102

Cell cycle promoting activity of JunB through cyclin A activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505053102

21 January 2018

The spindle checkpoint

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505053102

21 January 2018

Identifiers

DOI

10.1073/PNAS.0505053102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference