(Q47644235)

4 February 2018

title

Functional genomic responses to cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR(delta508) in the lung. (English)

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4 February 2018

main subject

cystic fibrosis

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transmembrane protein

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1 reference

Yan Xu

1

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4 February 2018

Cong Liu

series ordinal

2

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4 February 2018

Jean C Clark

series ordinal

3

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4 February 2018

Jeffrey A Whitsett

series ordinal

4

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4 February 2018

language of work or name

English

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publication date

2 February 2006

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4 February 2018

Journal of Biological Chemistry

published in

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4 February 2018

volume

281

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4 February 2018

page(s)

11279-11291

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4 February 2018

issue

16

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4 February 2018

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

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Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

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Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

21 January 2018

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Post-translational disruption of the delta F508 cystic fibrosis transmembrane conductance regulator (CFTR)-molecular chaperone complex with geldanamycin stabilizes delta F508 CFTR in the rabbit reticulocyte lysate.

21 January 2018

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The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 January 2018

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Principles of chaperone-assisted protein folding: differences between in vitro and in vivo mechanisms

21 January 2018

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In vivo newly translated polypeptides are sequestered in a protected folding environment

21 January 2018

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Peptidoglycan recognition protein tag7 forms a cytotoxic complex with heat shock protein 70 in solution and in lymphocytes.

21 January 2018

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The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis

21 January 2018

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Two enzymes in one; two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function

21 January 2018

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Inflammation and the regulation of glutathione level in lung epithelial cells.

21 January 2018

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Oxidative stress and regulation of glutathione in lung inflammation

21 January 2018

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Potential for antioxidant therapy of cystic fibrosis

21 January 2018

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Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation

21 January 2018

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New insights into the pathogenesis of cystic fibrosis: pivotal role of glutathione system dysfunction and implications for therapy

21 January 2018

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Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress

21 January 2018

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Protection against oxidative stress-induced cell death by intracellular platelet-activating factor-acetylhydrolase II.

21 January 2018

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Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for ar

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512072200

12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Apoptosis induced by the myelodysplastic syndrome-associated NPM-MLF1 chimeric protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512072200

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512072200

The human ubiquitin/52-residue ribosomal protein fusion gene subfamily (UbA52) is composed primarily of processed pseudogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Role of GADD153 (growth arrest- and DNA damage-inducible gene 153) in vascular smooth muscle cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

The transforming growth factor beta(1)-inducible transcription factor TIEG1, mediates apoptosis through oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512072200

Electrolyte transport in the mammalian colon: mechanisms and implications for disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

The subfornical organ is the primary locus of sodium-level sensing by Na(x) sodium channels for the control of salt-intake behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

NaX sodium channel is expressed in non-myelinating Schwann cells and alveolar type II cells in mice.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512072200

Cloning and characterization of 5'-flanking region of mouse non-selective cation channel 1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512072200

Expression of an mNSC1 in mammalian cells.

21 January 2018

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Cyclic AMP stimulates the gene expression of a non-selective cation channel, mNSC1, in pancreatic beta-cell line, MIN6.

21 January 2018

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Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

21 January 2018

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Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit

21 January 2018

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Differential roles of insulin receptor substrates in the anti-apoptotic function of insulin-like growth factor-1 and insulin

21 January 2018

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Insulin-like growth factor-binding protein 5 (IGFBP-5) interacts with a four and a half LIM protein 2 (FHL2).

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512072200

Activation of the coactivator four-and-a-half-LIM-only protein FHL2 and the c-fos promoter through inhibition of protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

The LIM-only protein DRAL/FHL2 interacts with and is a corepressor for the promyelocytic leukemia zinc finger protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512072200

Characterization of the cAMP response element of the cystic fibrosis transmembrane conductance regulator gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M512072200

A role for Sec1/Munc18 proteins in platelet exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

CFTR chloride channels are regulated by a SNAP-23/syntaxin 1A complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

c-Src is required for stimulation of gelsolin-associated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Tyrosine kinase c-Src constitutes a bridge between cystic fibrosis transmembrane regulator channel failure and MUC1 overexpression in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Protein phosphatase 2C dephosphorylates and inactivates cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Regulation of the CFTR channel by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Association of HSP105 with HSC70 in high molecular mass complexes in mouse FM3A cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Hsp105alpha suppresses Hsc70 chaperone activity by inhibiting Hsc70 ATPase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Characterization of human 12-lipoxygenase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Ketoconazole activates Cl- conductance and blocks Cl- and fluid absorption by cultured cystic fibrosis (CFPAC-1) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Fatty acids inhibit apical membrane chloride channels in airway epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Eicosanoids in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Fatty acid metabolism in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Association of cystic fibrosis with abnormalities in fatty acid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Involvement of hepatocyte nuclear factor 3 in endoderm differentiation of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Human-mouse genome comparisons to locate regulatory sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Microarray-based discovery of highly expressed olfactory mucosal genes: potential roles in the various functions of the olfactory system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

CFTR expression is regulated during both the cycle of the seminiferous epithelium and the oestrous cycle of rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

HNF1alpha is involved in tissue-specific regulation of CFTR gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Analysis of DNase-I-hypersensitive sites at the 3' end of the cystic fibrosis transmembrane conductance regulator gene (CFTR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Transcription of cystic fibrosis transmembrane conductance regulator requires a CCAAT-like element for both basal and cAMP-mediated regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

A regulatory element in intron 1 of the cystic fibrosis transmembrane conductance regulator gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca(2+)-ATPase gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Heat shock protein (Hsp) 40 mutants inhibit Hsp70 in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Anti-apoptotic effects of L-glutamine-mediated transcriptional modulation of the heat shock protein 72 during heat shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

Regulation of aldehyde reductase expression by STAF and CHOP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

In vivo cell-specific expression of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512072200

21 January 2018

Identifiers

DOI

10.1074/JBC.M512072200

1 reference

4 February 2018

PubMed ID

16455659

1 reference

4 February 2018